2014
DOI: 10.1002/14651858.cd008046.pub4
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Gonadotropin-releasing hormone agonist versus HCG for oocyte triggering in antagonist-assisted reproductive technology

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Cited by 254 publications
(215 citation statements)
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References 87 publications
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“…Therefore, the routine use of a GnRH agonist as the lone trigger for final 4 oocyte maturation in fresh IVF autologous cycles was discouraged. It was considered that it could be useful for women who choose to avoid fresh transfers, women who donate oocytes to recipients or women who wish to freeze their eggs for later use in the context of fertility preservation [3]. However, it should be noted that the authors did not recognize that luteal support was the variable responsible for lower pregnancy rates because the luteal phase support differed among studies included in the Cochrane analysis.…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, the routine use of a GnRH agonist as the lone trigger for final 4 oocyte maturation in fresh IVF autologous cycles was discouraged. It was considered that it could be useful for women who choose to avoid fresh transfers, women who donate oocytes to recipients or women who wish to freeze their eggs for later use in the context of fertility preservation [3]. However, it should be noted that the authors did not recognize that luteal support was the variable responsible for lower pregnancy rates because the luteal phase support differed among studies included in the Cochrane analysis.…”
Section: Introductionmentioning
confidence: 99%
“…52 2014 yılındaki bir Cochrane meta-analizinde GnRH agonistleri ile ovulasyonun tetiklenmesi HCG ile karşılaştırıldı-ğında OHSS insidansında azalma ile birlikte daha düşük gebelik ve canlı doğum oranları ile ilişkili bulunmuştur. 53 OPU işleminden 35-37 saat öncesinde eş zamanlı olarak standart doz HCG'ye ek olarak GnRH agonist uygulanması 'dual trigger' olarak adlandı-rılmaktadır. Lin ve ark.…”
Section: Hcg (üRiner/recombinant) R-lh Gnrh Agonistleriunclassified
“…GnRH agonist triggering has been associated with luteal phase defects, presumably due to excessive negative steroid feedback [37][38][39]. Two consecutive Cochrane reviews by the same author state that: BGnRH agonist triggering is associated with a lower ongoing pregnancy rate compared with conventional hCG^ [29,40]. This conclusion was qualified as premature and mistaken based on the following: (1) Cochrane reviews should not be conducted in the research phase when new concepts are being developed, and (2) the authors missed the fact that the variable that affects results is luteal phase support itself and not the use of GnRH agonist trigger for final oocyte maturation [39].…”
Section: Freeze-all-why?mentioning
confidence: 99%