Purpose To compare the diagnostic performances of contrast material-enhanced spectral mammography and breast magnetic resonance (MR) imaging in the detection of index and secondary cancers in women with newly diagnosed breast cancer by using histologic or imaging follow-up as the standard of reference. Materials and Methods This institutional review board-approved, HIPAA-compliant, retrospective study included 52 women who underwent breast MR imaging and contrast-enhanced spectral mammography for newly diagnosed unilateral breast cancer between March 2014 and October 2015. Of those 52 patients, 46 were referred for contrast-enhanced spectral mammography and targeted ultrasonography because they had additional suspicious lesions at MR imaging. In six of the 52 patients, breast cancer had been diagnosed at an outside institution. These patients were referred for contrast-enhanced spectral mammography and targeted US as part of diagnostic imaging. Images from contrast-enhanced spectral mammography were analyzed by two fellowship-trained breast imagers with 2.5 years of experience with contrast-enhanced spectral mammography. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value were calculated for both imaging modalities and compared by using the Bennett statistic. Results Fifty-two women with 120 breast lesions were included for analysis (mean age, 50 years; range, 29-73 years). Contrast-enhanced spectral mammography had similar sensitivity to MR imaging (94% [66 of 70 lesions] vs 99% [69 of 70 lesions]), a significantly higher PPV than MR imaging (93% [66 of 71 lesions] vs 60% [69 of 115 lesions]), and fewer false-positive findings than MR imaging (five vs 45) (P < .001 for all results). In addition, contrast-enhanced spectral mammography depicted 11 of the 11 secondary cancers (100%) and MR imaging depicted 10 (91%). Conclusion Contrast-enhanced spectral mammography is potentially as sensitive as MR imaging in the evaluation of extent of disease in newly diagnosed breast cancer, with a higher PPV. RSNA, 2017.
Background: Adnexal torsion accounts for 2.7% of gynecological emergencies. Early diagnosis can help prevent irreversible damage to ovary. Objective of this study was to analyze the clinical, radiological and pathological characteristics of surgically proven cases of ovarian torsion. Methods: Observational study was carried out from January 2006 to June 2014. Medical records of 38 cases of adnexal torsion were selected and analyzed retrospectively for age, parity, risk factors, clinical presentation, presence of leukocytosis, gray scale ultrasound and colour Doppler features, management, pathological results and postoperative outcome. Results: Adnexal torsion occurred most commonly in reproductive age group (mean 27.89 years) of whom 3 were pregnant. 42% had known risk factors commonly prior pelvic surgery (52.63%) and prior tubal ligation (31.58%). Symptoms include sudden abdominal or pelvic pain (94.74%), vomiting (60.53%) and fever (21.05%). Gray scale USG showed mixed echogenic mass (36.84%), homogenously echogenic cyst (34.21%) anechoic cyst (26.32%) and free fluid (23.68%). Doppler showed absent arterial and venous flow in 52.63%. Cases were managed by detorsion & cystectomy (42.11%), unilateral salpingooophorectomy (47.37%), bilateral salpingooophorectomy (5.26%) and TAH with BSO (5.26%). Histopathology revealed benign serous epithelial tumors (31.58%), mucinous tumors (21.05%), mature teratoma (10.53%), corpus luteal cyst (5.26%), follicular cyst (2.63%) paraovarian cyst (13.16%), endometriotic cyst (2.63%) and ovarian hemangioma (2.63%). Conclusions: High index of suspicion &prompt surgical intervention is necessary to preserve ovarian function even if Doppler shows vascularity. Though detorsion and cystectomy is the choice, salpingooophorectomy may be needed in infracted ovaries and older women. Higher incidence of serous & mucinous tumors in our study suggests reappraisal of ovary sparing surgery for all patients as advocated by few.
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