Peste des petits ruminants (PPR) disease was confirmed in West African Dwarf goats. They were managed symptomatically with antibiotics and antidarrhoeics. Following clinical recovery, faeces were collected every week from 40 recovered goats to monitor excretion of the PPR virus haemagglutinins in their faeces. All the 40 recovered goats shed the PPR virus haemagglutinins for 11 weeks post recovery. Nine goats (22.5%) continued shedding the viral antigen 12 weeks post recovery. There was correlation between weekly mean haemagglutination titre of the PPR virus and time post recovery with r = -0.7504 (p < 0.01).

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Effect of a synthetic Aluminium-Magnesium Silicate (AMS) on Newcastle Disease Virus (NDV) was tested. Equal amounts, of the AMS and of NDV, on a volume to weight (v/w) basis, were incubated for one hour at room temperature, and then centrifuged. The supernatant was tested for NDV titre. Portions of a virulent NDV were similarly incubated with the AMS, and their supernatants tested for morbidity rates on infected chicks. Also, two groups of chicks were infected with virulent NDV intramuscularly (I/m), and by introduction of infected chicks, respectively. Their subgroups were treated by administering AMS through drinking water, to assess its effect on mortality. Incubating NDV with AMS, reduced the viral titre from mean HA, 613 ±86 to 4. 5 ±0.72 (P < 0.05). Also, incubating virulent NDV with the AMS, reduced its morbidity rate from 100% to 20% (P< 0.05) when incubated once, and from 100% to zero, when incubated twice. NDV-infected chicks treated with AMS, had same 100% mortality as the controls, when route of infection was I/m (P > 0.05) but when infection was by introduction of infected chicks, mortality reduced from 20% to zero (P < 0.05).These results suggest AMS as NDV's antiviral agent.

To treat resistant Escherichia coli infection in chicks, Ampicillin was stabilized with a synthetic aluminum-magnesium silicate (AMS) to prolong its bioavailability. Its dose was also reduced to minimize adverse side effects. Vitamins A, C, E and Selenium levels in the chicks' feeds were increased to enhance immune response of the chicks. E. coli coloning forming units, per ml of bile of the chicks, treated with Ampicillin and with Ampicillin in AMS, were: 228800.00 ± 90103.50 and 134500.00 ± 44937.97 at 10 mg/kg, 104400.00 ± 36024.44 and 34800.00 ± 8014.97 at 7.5 mg/kg, 198400.00 ± 129301.80 and 156800.00 ± 109392.70 at 5 mg/kg. Mean bacterial loads of the untreated groups, fed normal feed and those fed the fortified feed were 824400.00 ± 322424.80 and 534800.00 ± 277832.80. At 7.5 mg/kg. Ampicillin in the AMS, effectively (P < 0.05) treated resistant E. coli infection in chicks, fed immunestimulants, with the infection rate reduced by 95.8%.

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