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The aim of this study is to prove the effectiveness of IR spectroscopy as an identification test able to discriminate between mineral compounds in mixtures. This work is concerned with the physical characterisation of purified bentonite, bentonite in organic mixtures and organic excipients, and mineralized organic mixture containing bentonite using FT-IR spectroscopy. The different spectra were compared with each other in order to determine fingerprints of bentonite represented by bands located at 3632 cm−1 and 3437 cm−1. The analysis of the spectra of the nonmineralized mixture demonstrates the presence of two bands at 1454 and 2928 cm−1, superimposed on those of the excipients and which disappear after 2 hours of mineralization at 500°C. Finally, we notice a displacement of the stretching band of H2O to the right with increasing the proportion of the excipients.

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Since they are natural, plants are wrongly considered nondangerous; therefore people used them in various contexts. Each plant is used alone or in mixture with others, where knowledge and the requirements of preparation and consumption are not mastered. Thus, intoxications due to the use of plants have become more and more frequent. The reports of intoxications made at the Antipoison Center and Pharmacovigilance of Morocco (ACPM) support this finding, since the interrogations suffered by the victims show that the use of plants is practiced irrationally, anarchically, and uncontrollably. Faced by the increase of these cases of poisoning in Morocco, it seemed necessary to investigate the nature of poisonous plants, their monographs, and the chemicals responsible for this toxicity.

Many dyes are contained in plants and are used for coloring a medium. They are characterized by their content of dyes molecules. They stimulate interest because they are part of a sustainable development approach. There are several chemicals families of plant dye which are contained in more than 450 plants known around the world. In this article, a study based on literature allowed us to realize an inventory of the main dyes plants potentially present in Morocco. A list of 117 plants was established specifying their botanical families, chemical Composition, Colors and parts of the plant used.

Introduction: During the reconstitution of a drug and during its storage, there are risks of interactions between the drug and the bag used for the preparation. Polyvinyl chloride is a material used in the manufacture of a large part of chemotherapy infusion bags. It is subject to many interactions like sorption of drugs and release of phthalate additives. Material and Methods: Seven anticancer drugs used in pediatric oncology were involved in our study. After reconstitution of the anticancer agents in polyvinyl chloride bags, the adsorption phenomenon between the container and the contents is evaluated by infrared spectroscopy by analyzing the inner surface of the polyvinyl chloride. Subsequently, for the anticancer agents which exhibited an adsorption-container-content, the analysis was carried out by ultravioletvisible spectrophotometry in order to examine the kinetics of the concentration of reconstituted anticancer drugs. Results: All the polyvinyl chloride bags gave a spectrum identical to the spectrum of the reference bag, except the bags used to reconstitute etoposide whose spectra showed 12 additional peaks. With the absorbances measured by ultraviolet-visible spectrophotometry at different times, the analysis of variance statistical analysis shows that there is a significant difference in absorbances between t 0 and all the other measurement times. Conclusion: This study testifies to the existence of a container-content interaction between etoposide and polyvinyl chloride. Thus, reconstitution of etoposide for intravenous infusion into a polyvinyl chloride bag should be used immediately. For etoposide preparations intended for storage beyond 24 h, it is recommended to use a container other than the polyvinyl chloride bag.

For thousands of years, truffles have been used as essential foods in different cultures around the world because of their rich nutritional value and their pleasant and characteristic smell. We have studied the effect of truffles (Tirmania Nivea and Tirmania Pinoyi) extracts on the antioxidant stress properties issued from the Moroccan desert. Antioxidant and anti-free radical activities were studied using three analytical methods: trapping capacity of 1,1-diphenyl-2-picrylhydrazyl, phosphomolybdate, and reducing ferric antioxidant capacity; in addition, phenol and flavonoid levels were measured. The results of the FRAP, DPPH and PPM tests of T. Nivea were respectively 4.112±0.217, 0.142±0.006, 2.235±0.110 mg/mL for methanols and 3.424±0.034, 0.137±0.025, 0.858±0.010 mg/mL for ethyl acetate extracts. The results of the tests of T. pinoyi were respectively 3.670±0.572, 0.102±0.004, 0.907±0.014 mg/mL for methanols and 3.404±0.096, 0.080±0.003, 0.693±0.057 mg/mL for ethyl acetate extracts. For this work, we propose a valorization of the Moroccan truffle in the prevention of oxidative stress.