Viral hepatitis is a serious public health problem affecting billions of people globally. Limited information is available on this issue inCote d'Ivoire. The objectives of this study were to determine the prevalence and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) during an active screening campaign in Abidjan. A cross-sectional study was conducted at Pasteur Institute of Cote d'Ivoire from July 2015 to February 2016. The ethical clearance for this study was obtained from the National Ethical and Research Committee. An informed written consent was obtained from the participants of the study and administered a questionnaire related to the socio demographical information and risk factors of a possible route transmission HBV and hepatitis C virus (HCV). Blood samples were collected for the detection of HBS Ag, Ab-HBc IgG and Ab-HCV. Serological analyses were performed by Cobase 601 (Roche R ). Data were analyzed by R software. A total of 1801 patients were recruited; among them 138 children (7.7%) aged from 0 to 15 years and 1663 adults (92.3%). The sex ratio was 1.2 (964/837). The overall prevalence of HBsAg was 30. 9% (557/1801) and 41.1% (702/1708) for Ab-HBc IgG. About HCV, the overall prevalence rate was 5.3% (95/1687), none of the children was HCV positive. The co-infection HBV/HCV rate was 0.95% (16/1687). HCV was associated with age and sexual risk behaviors. HBV was associated with gender, youth, sexual risk behaviors, and scarification. Our findings revealed a high prevalence of HBV. The measures to reduce the disease and its load transmission must be strengthened.

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The seroprevalence of herpes simplex virus II (HSV2) was investigated from April, 2011 to May, 2012 among 170 pregnant women attending consultation in the urban health training Yopougon-Attié, Abidjan (Côte d'Ivoire). The anti-HSV2 immunoglobin G (IgG) antibodies were detected by the principle of indirect enzyme-linked immunosorbent assay (ELISA) using the Diagnostic Automation ELISA ® kit. Human immunodeficiency virus (HIV) serology was performed using rapid testing according to the national algorithm. Anti HSV2 IgG serology was positive in 96.5% (164/170) of women. HSV2/HIV coinfection was found in 6.7% (11/164) of parturients. No socio-epidemiological factor was related to the seroprevalence of HSV2 infection. Data from this study suggest a serological surveillance of pregnant women, in particular looking for a recent infection by assaying IgM or by real-time quantitative HSV DNA polymerase chain reaction (PCR). Indeed, the high prevalence of HSV2 in this population requires the implementation of a protocol in collaboration with the actors for the health of mother and child.

The aim of this study was to highlight the role of urban pollution on nutrient levels changes in lagoon environment under influence of hydroclimate. The ratio of biological and chemical oxygen demand BOD/COD was 0.7 with a significant average oxidizable matter charge (320 mg/L). Evolution of COD, BOD, NTK (total nitrogen) and Pt (total phosphorus) from 3.4 mm to 84.5 mm of rainfall, range from respectively, <50 mg/L, <50 mg/L, <0.3 mg/L, 48 mg/L to 419.75 mg/L, 275 mg/L, 1.875 mg/L, 4.55 mg/L. The (bio) availability of phosphate, ammonium and/or nitrate in water column changed depending on environmental conditions. The evolution of these pollutions effects may jeopardize the sustainability of the Abidjan lagoon system.

Non Poliovirus enteroviruses (NPEV) are infectious agents which can determine various infections. They are more and more isolated within the context of the surveillance of acute flaccid paralysis (AFP) and raise a problem of antigenic identification. In Côte d'Ivoire the serotypes of NPEV circulating are unknown. In order to determine the epidemiological and virology characteristics of human (NPEV) stemming from virology investigations from 1996 to 2004, enteroviruses strains isolated from stools and from cerebrospinal fluid have been analysed. The biological products have been tested according to the procedures recommended by the World Health Organisation (WHO) within the context of the virology surveillance of acute flaccid paralysis and the antigenic identification by seroneutralization and serotyping has been done. Out of 144 isolates obtained from 10187 specimens, 637 were Poliovirus strains and 807 NPEV strains (7.9%). Among them 16.3% have been isolated during carrier studies and 83.7% were associated with cases of AFFP Out of the 807 strains of NPE, 218 strains have been tested by serotyping and the serotype of 77 strains (35.32%) has been determined: Coxsackievirus B (41.6%) and different serotypes of Echovirus (58.4%). The proportion of untypable strains (62.3%) confirms the difficulties to identify NPEV with the conventional available reagents. The molecular diagnosis is becoming necessary in order to establish a list of the serotypes of NPEV circulating and associated with clinical features in the country