A very high frequency of hepatitis B and C virus infections during an active screening campaign in Abidjan

Abstract

Viral hepatitis is a serious public health problem affecting billions of people globally. Limited information is available on this issue inCote d'Ivoire. The objectives of this study were to determine the prevalence and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) during an active screening campaign in Abidjan. A cross-sectional study was conducted at Pasteur Institute of Cote d'Ivoire from July 2015 to February 2016. The ethical clearance for this study was obtained from the National Ethical and Research Committee. An informed written consent was obtained from the participants of the study and administered a questionnaire related to the socio demographical information and risk factors of a possible route transmission HBV and hepatitis C virus (HCV). Blood samples were collected for the detection of HBS Ag, Ab-HBc IgG and Ab-HCV. Serological analyses were performed by Cobase 601 (Roche R ). Data were analyzed by R software. A total of 1801 patients were recruited; among them 138 children (7.7%) aged from 0 to 15 years and 1663 adults (92.3%). The sex ratio was 1.2 (964/837). The overall prevalence of HBsAg was 30. 9% (557/1801) and 41.1% (702/1708) for Ab-HBc IgG. About HCV, the overall prevalence rate was 5.3% (95/1687), none of the children was HCV positive. The co-infection HBV/HCV rate was 0.95% (16/1687). HCV was associated with age and sexual risk behaviors. HBV was associated with gender, youth, sexual risk behaviors, and scarification. Our findings revealed a high prevalence of HBV. The measures to reduce the disease and its load transmission must be strengthened.

Seroprevalence of Hepatitis B and C Viruses among Human Immunodeficiency Virus Infected Patients Accessing Healthcare in Federal Medical Centre, Keffi, Nigeria

“…There was no statistically significant difference between viral infections and scarification marks (p > 0.05). Such was also reported in a similar study in Cote d'voire [12]. There was no statistically significant association between locality and the viral infections (p > 0.05).…”

“…, 7.9% in Abuja[11], 3.9% in Lagos[9] and 12.3% in Kano[10] among HIV patients. Similar studies from other countries found 30.9% in Cote d'voire[12], 6.0% in Kenya[7] 1.16% in Pakistan[13], 10.3% in Brazil[1]. These differences in prevalence might be as a result of geographical location, population and sensitivity of tests used for screening.…”

“…5%], those with no history of blood transfusion and those with no history of alcohol intake. Pennap et al [16] in Nigeria, KouassiM'Bengue et al [12] in Cote d'voire and Agyeman and Ofori-Asenso, [17] in Ghana reported same in a similar study.…”

Prevalence of Some Opportunistic Infections (OIs) and Co-infections among HIV-Infected Persons in Port Harcourt, Nigeria

“…Viral hepatitis is also a serious public health concern that affects billions of people globally [16]. More than 240 million people have HBV globally, and the majority occur in developing countries [16,17], such as Nigeria.…”

“…Viral hepatitis is also a serious public health concern that affects billions of people globally [16]. More than 240 million people have HBV globally, and the majority occur in developing countries [16,17], such as Nigeria. Of the total number of persons living with HIV, about 7.4% are co-infected with HBV while 1% of persons living with HBV are also infected with HIV [18].…”