Viral hepatitis is a serious public health problem affecting billions of people globally. Limited information is available on this issue inCote d'Ivoire. The objectives of this study were to determine the prevalence and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) during an active screening campaign in Abidjan. A cross-sectional study was conducted at Pasteur Institute of Cote d'Ivoire from July 2015 to February 2016. The ethical clearance for this study was obtained from the National Ethical and Research Committee. An informed written consent was obtained from the participants of the study and administered a questionnaire related to the socio demographical information and risk factors of a possible route transmission HBV and hepatitis C virus (HCV). Blood samples were collected for the detection of HBS Ag, Ab-HBc IgG and Ab-HCV. Serological analyses were performed by Cobase 601 (Roche R ). Data were analyzed by R software. A total of 1801 patients were recruited; among them 138 children (7.7%) aged from 0 to 15 years and 1663 adults (92.3%). The sex ratio was 1.2 (964/837). The overall prevalence of HBsAg was 30. 9% (557/1801) and 41.1% (702/1708) for Ab-HBc IgG. About HCV, the overall prevalence rate was 5.3% (95/1687), none of the children was HCV positive. The co-infection HBV/HCV rate was 0.95% (16/1687). HCV was associated with age and sexual risk behaviors. HBV was associated with gender, youth, sexual risk behaviors, and scarification. Our findings revealed a high prevalence of HBV. The measures to reduce the disease and its load transmission must be strengthened.

IntroductionToutes les sténoses symptomatiques de l’œsophage peuvent être dilatées par voie endoscopique. Nous évaluons l'apport des moyens endoscopiques dans la prise en charge de la dilatation œsophagienne pour sténose caustique de l’œsophage (SCO) au Mali.MéthodesIL s'agissait d'une étude descriptive et prospective réalisée dans le service de chirurgie thoracique à l'hôpital du Mali. Au total 46 dossiers cliniques de patients on été enregistrés et subdivisés en 4 groupes en fonction de la topographie des lésions cicatricielles. Le nombre de cas d'assistance endoscopique réalisé a été déterminé afin de comprendre l'apport des moyens endoscopiques dans le succès de la dilatation des SCO. Pour les 2 différentes méthodes de dilatation utilisées, le résultat du traitement et le coût ont comparés.RésultatsLa FOGD a été utilisée dans 19 cas (41.30%) de dilatation avec la bougie de Savary Guillard et dans 47.82% des cas dans la dilatation de Lerut. La vidéo-laryngoscopie a été utilisé 58.69% des cas de dilatation à la bougie de Lerut. Le passage de guide métallique et / ou de fil-guide a été réalisée dans 39.13% avec la vidéo laryngoscopie et dans 58.68% avec la FOGD. Dans la comparaison des deux méthodes, il existe une différence significative dans la survenue des complications (p=0.04075), l'anesthésie générale (p=0.02287), l'accessibilité à la méthode (p=0.04805) et la mortalité (p=0.00402).ConclusionLa SCO est une pathologie grave et sous évaluée au Mali. Les moyens endoscopiques contribuent considérablement au succès de la dilatation œsophagienne pour sténose caustique dans les différentes méthodes utilisées.

IntroductionHuman Papillomaviruses (HPV) are small virus non-enveloped double-stranded circular DNA responsible of genital warts papilloma, precancerous lesions and cancers (cervix, vulva). In Côte d’Ivoire and many lower middle and incomes countries cervical cancer screening program based on visual inspection methods become the gold standard because cytology has shown many limits. This study aims to detect HPV DNA on women attending for cervical cancer screening program based on visual inspection by acid acetic and lugol (IVA/IVL).MethodsFrom March to December 2015, endocervical secretions from women attending cervical screening by IVA were submitted to HPV determination with PCR. HPV DNA was amplified using PGMY09/11 primers which generated 450 base pairs at the L1 region. The samples harbouring HPV DNA were genotyped using the multiplex PCR with HPV 16, 18, 31, 33, 35, 45 and 51 primers.ResultsThe medium age of population was 32 years old. On 388 women enrolled in a visual inspection with acetic acid (VIA) program 5.8% were positif. HPV DNA was obtained in 9.02% of the population. A total of 31 (88.57%) specimens harbouring HPV DNA were genotypes using multiplex PCR versus 11.43%, which were not genotyped using HPV 16,18, 31, 33, 35, 45 and 51 by multiplex PCR. HPV genotyping gave 63 differents HPV with 28.57% who had a single infection while 71.43% have a multiple infection. HPV genotypes prevalence were the followed: HPV 16 (28.57%), HPV 18 (23.80%), HPV35 (19.04%), HPV 45 (19.04%), HPV 51 (3.17%) and HPV 33 (1.58%). By using PCR as gold standard VIA sensibility was 16.12% and the specificity 95.45%.ConclusionHPV circulate in Cote d’Ivoire in women attending for cervical cancer screnning by visual inspection with acetic acid or lugol. Visual inspection with acetic acid or lugol seem to have a good specificity. HPV Genotypes 16 and 18 included in the vaccine available seem to be the most prevalent.

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Ischemic strokes have varying etiologies and multiple locations. Some locations are much rarer than others and just as difficult to diagnose. This is the case of the ischemic bi-thalamic stroke, attributable to the Percheron artery occlusion that we report in a 33-year-old woman with a history of taking estrogen-progestin. The lesion diagnosis could only be possible thanks to the performance of brain MRI, thus testifying to the diagnostic difficulties observed. Etiological research has shown dyslipidemia. The length of stay was 88 days. At the end of intensive care, the patient was conscious, not deficient and did not present memory disorders.