This study showed no evidence of benefit from the prophylactic use of low-energy laser in children and adolescents with cancer treated with chemotherapy when optimal dental and oral care was provided.
El carcinoma verrucoso es una variación de bajo grado de malignidad del carcinoma de células escamosas oral, y la mayoría surge en la mucosa oral de individuos que mascan tabaco de forma crónica (6,8, 10). Estas lesiones encontradas predominantemente en hombres, con más de 55 años de edad (edad promedio de 65 a 70 anos) y las regiones de mayor frecuencia en mucosa bucal incluyen vestíbulo mandibular, mucosa yugal y palato duro (6,8). La lesión aparece como una placa espesa, difusa, bien demarcada e indolora, con proyecciones superficiales papilares o verruciformes. Microscópicamente, se observa la presencia de crestas interpapilares anchas y alargadas y producción abundante de ceratina (2). La metástasis es un evento raro en los carcinomas verrucosos (6,8,9). El tratamiento de elección es la excisión quirúrgica, asociada o no a la radioterapia. Los autores relatan un caso clínico de una paciente de 13 años de edad con lesión comprometiendo todo lo vermellion del labio inferior. El tratamiento inicial propuesto fue la radioterapia asociado a la quimioterapia, decido a la edad de la paciente, localización y extensión de la lesión. Después de una dosis total de 70Gy, hubo la regresión total de la lesión. Siendo así, el tratamiento del carcinoma verrucoso asociando a la radioterapia y quimioterapia se mostró adecuado en este caso.Palabras clave: Carcinoma Verrucoso Oral, Radioterapia, paciente joven. ABSTRACTThe verrucous carcinoma is a low grade variant of oral squamous cell carcinoma, and it mostly appears in the oral mucosa of individuals who chew tobacco chronically 6,8,10. The lesions are mainly found in men over 55 years old (average age 65 to 70 years) and the most common regions in the oral mucosa include the mandibular vestibule, jugal mucosa and hard palate 6,8. The lesion appears as a well-defined painless diffuse thick plaque with superficial papillary or verruciform projections. Under the microscope the presence of wide elongated interpapilIary ridges and copious keratin production are observed2. Metastasis is a rare event in verrucous carcinomas 6,8,9. The treatment of choice is surgical excision, optionally combined with radiotherapy. The authors report a c1inical case of a 13-year-old patient with a lesion compromising the whole lower Iip vermilion. The initial treatment proposed was radiotherapy combined with chemotherapy, due to the patient's age and the localization and extent of the lesion. After a total dose of 70Gy, full regression of the lesion took place. Thus, treatment of verrucous carcinoma by combining radiotherapy with chemotherapy proved satisfactory in this case.
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