Muscle quality is an important component of the functional profile of the elderly, and previous studies have shown that both muscle quantity and quality independently contribute to muscle strength of the elderly. This study aimed to verify the association between quadriceps femoris muscle quality, analyzed by specific tension and echo intensity (EI), and rate of torque development (RTD) of the knee extensor muscles with the functional performance in elderly active women. Forty-five healthy, active elderly women (70.28 ± 6.2) volunteered to participate in this study. Quadriceps femoris muscle thickness and EI were determined by ultrasonography. Knee extension isometric peak torque and RTD were obtained from maximal isometric voluntary contraction curves. The 30-s sit-to-stand-up (30SS) test and usual gait speed (UGS) test were applied to evaluate functional performance. Rectus femoris EI presented a significant negative correlation with 30SS (r = -0.505, P < 0.01), UGS (r s = -0.347, P < 0.05), and isometric peak torque (r = -0.314, P < 0.05). The quadriceps femoris EI correlated negatively with 30SS (r = -0.493, P < 0.01) and isometric peak torque (r = -0.409, P < 0.01). The EI of the quadriceps femoris and all quadriceps muscle portions significantly correlated with RTD. RTD significantly correlated with physical performance in both functional tests (30SS = r = 0.340, P < 0.05; UGS = r s = 0.371, P < 0.05). We concluded that muscle EI may be an important predictor of functional performance and knee extensor power capacity in elderly, active women.

Increased proportion of non-contractile elements can be observed during aging by enhanced skeletal muscle echo intensity (EI). Studies have demonstrated that an increase in rectus femoris EI may affect physical performance. However, it is still unknown whether the whole quadriceps femoris EI (QEI) influences strength, power, and functional capacity of an older population. Therefore, the aim of the present study was to determine the correlation between QEI, the four individual quadriceps portions EI, and muscular performance of older men. Fifty sedentary healthy men (66.1 ± 4.5 years, 1.75 ± 0.06 m, 80.2 ± 11.0 kg) volunteered for the present study. The QEI and EI of the four quadriceps portions were calculated by ultrasound imaging. Knee extension one repetition maximum (1RM), isometric peak torque (PT), and rate of torque development (RTD) were obtained as measures of muscular strength. Muscular power was determined by knee extension with 60 % of 1RM and countermovement jump (CMJ). The 30-s sit-to-stand test was evaluated as a functional capacity parameter. QEI and all individual EI were correlated to functional capacity and power during CMJ (p ≤ 0.05), but rectus femoris EI was not related to knee extension average power (p > 0.05). There were significant correlations between all EI variables, 1RM, PT, and RTD at 0.2 s (p ≤ 0.05), but only vastus medialis EI and QEI were correlated to RTD at 0.05 s (p ≤ 0.05). The results of the present study suggest that QEI is related to muscular power and functional capacity of older subjects, but the EI of some individual quadriceps portions may underestimate the correlations with muscular performance.

Frequency of 1-6 sessions per week, training volume of 1-3 sets of 6-15 repetitions and intensity of 30-70%1-RM promoted significant enhancements on muscle strength, muscle power, and functional outcomes. Therefore, in agreement with previous studies, we suggest that supervised and controlled RT represents an effective intervention in frailty treatment.

This study showed no evidence of benefit from the prophylactic use of low-energy laser in children and adolescents with cancer treated with chemotherapy when optimal dental and oral care was provided.

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These results indicate that QEI was the strongest contributor to functionality of nonactive older men, suggesting that QEI may be an alternative tool for screening of muscle impairment that leads to decreased functional performance in this population. Muscle Nerve 55: 9-15, 2017.

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Botton, CE, Radaelli, R, Wilhelm, EN, Rech, A, Brown, LE, and Pinto, RS. Neuromuscular adaptations to unilateral vs. bilateral strength training in women. J Strength Cond Res 30(7): 1924-1932, 2016-Considering the bilateral deficit, the sum of forces produced by each limb in a unilateral condition is generally greater than that produced by them in a bilateral condition. Therefore, it can be speculated that performing unilateral strength exercises may allow greater training workloads and subsequently greater neuromuscular adaptations when compared with bilateral training. Hence, the purpose of this study was to compare neuromuscular adaptations with unilateral vs. bilateral training in the knee extensor muscles. Forty-three recreationally active young women were allocated to a control, unilateral (UG) or bilateral (BG) training group, which performed 2 times strength training sessions a week for 12 weeks. Knee extension one repetition maximum (1RM), maximal isometric strength, muscle electrical activity, and muscle thickness were obtained before and after the study period. Muscle strength was measured in unilateral (right + left) and bilateral tests. Both UG and BG increased similarly their unilateral 1RM (33.3 ± 14.3% vs. 24.6 ± 11.9%, respectively), bilateral 1RM (20.3 ± 6.8% vs. 28.5 ± 12.3%, respectively), and isometric strength (14.7 ± 11.3% vs. 13.1 ± 12.5%, respectively). The UG demonstrated greater unilateral isometric strength increase than the BG (21.4 ± 10.5% vs. 10.3 ± 11.1%, respectively) and only the UG increased muscle electrical activity. Muscle thickness increased similarly for both training groups. Neither group exhibited pretesting 1RM bilateral deficit values, but at post-testing, UG showed a significant bilateral deficit (-6.5 ± 7.8%) whereas BG showed a significant bilateral facilitation (5.9 ± 9.0%). Thus, performing unilateral or bilateral exercises was not a decisive factor for improving morphological adaptations and bilateral muscle strength in untrained women. Unilateral training, however, potentiate unilateral specific strength gains.