The influence of 210Pb on the effective half life of 210Po in various organs of the male rat was investigated. Male rats were injected with an equilibrium solution of RaDEF. Rats were sacrificed over 140 days post injection and skull, femur, spine, kidney, gonads, spleen, liver, lungs, blood and heart removed, weighed and analyzed for their 210Po and zloPb content. The data indicate that soft tissue half life and distribution values for zlOPo will be influenced by thc release of 2lOPo from the bone compartment. The results bring into question the MPC values for decay chains (i.e. RaDEF decay chain) in which daughter products can be redistributed to other organs thereby increasing the radiation dose to these organs.
A computer algorithm for designing sheet lead tissue compensators is described. Corrections are made for scatter within the radiation field as well as the shape of the patient for the mantle fields used in treating Hodgkin's disease. The method was tested experimentally with a phantom and found to be clinically acceptable. The advantages of employing this technique with parallel opposed fields are emphasized.
The ld50 values were determined for rats exposed to 100–250 kvp x-rays for doses expressed ‘in air’ and ‘in tissue.’ Dose measurements were made in animal tissue. For the ld50 ‘in tissue’ doses, the relative effectiveness was approximately one for all qualities. For the experimental conditions of the study, it seems that mid-line tissue dose may be the proper parameter for acute lethality in rats exposed to x-radiations having different depth dose distributions.
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