Mid-Line Tissue Dose and Lethality in X-Irradiated Rats

Abstract

The ld50 values were determined for rats exposed to 100–250 kvp x-rays for doses expressed ‘in air’ and ‘in tissue.’ Dose measurements were made in animal tissue. For the ld50 ‘in tissue’ doses, the relative effectiveness was approximately one for all qualities. For the experimental conditions of the study, it seems that mid-line tissue dose may be the proper parameter for acute lethality in rats exposed to x-radiations having different depth dose distributions.