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This study indicates that SIBO in diabetes patients may be due to delayed OCTT.

I956 5. The countercurrent-distribution technique has also been used for studies of the action of aqueous HCI on protoporphyrin and its methyl ester. We thank Professor C. Rimington, F.R.S., for his continuous encouragement and support and Miss B. E. Tooth for technical assistance. We are grateful to B. Lewis and Co. for generous supplies of chicken blood. During part of the time that this work was carried out, one of us (J.E.F.) held a Foulerton Research Fellowship of the Royal Society. The Nuffield Unit is supported by a grant from the Nuffield Foundation to Professor C. Rimington.

NAC protects young rats against RMP-induced oxidative hepatic injury.

A new antibiotic, naphthyridinomycin, was isolated in crystalline form from the culture filtrate of Streptomyces lusitanus AY B-1026. The antibiotic is active against a large number of both gram-positive and gram-negative bacteria, and inactive against Candida albicans, Trichophyton granulosum and Microsporum gypseum. The antibiotic is toxic in mice. A new strain of streptomycete was isolated from a Easter Island (Rapa Nui) soil sample. Cultures of this microorganism were found to produce marked antibacterial activity and to bring about strong morphological changes in Escherichia coli. The active principle was isolated

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