Take Home Message: Lung Clearance Index (LCI) in the early years was associated with LCI during adolescence in children with Cystic Fibrosis. Preschool LCI may help to identify a children in whom treatment could be intensified. Author contributions: PA, AB, AW, CMO and JS were responsible for the conception and design of study. Children with CF were recruited by the paediatric respiratory consultants participating in the LCFC, including PA, AB, SC, CP. Lung function measurements at adolescence were performed by JD and ER. Collation of data between preschool, school age and adolescent follow up was performed by SL, JD, ER and GD. AC provided technical advice on imaging and undertook CT scoring. SS led on statistical analysis with analyses also performed by GD and AW. GD and SS drafted the manuscript; all remaining authors revised and approved the manuscript for intellectual content before submission.

Primary ciliary dyskinesia (PCD) is a rare heterogenous condition that causes progressive suppurative lung disease, chronic rhinosinusitis, chronic otitis media, infertility and abnormal situs. ‘Better Experimental Approaches to Treat Primary Ciliary Dyskinesia’ (BEAT-PCD) is a network of scientists and clinicians coordinating research from basic science through to clinical care with the intention of developing treatments and diagnostics that lead to improved long-term outcomes for patients. BEAT-PCD activities are supported by EU funded COST Action (BM1407). The second BEAT-PCD conference, and third PCD training school were held jointly in April 2017 in Valencia, Spain. Presentations and workshops focussed on advancing the knowledge and skills relating to PCD in: basic science, epidemiology, diagnostic testing, clinical management and clinical trials. The multidisciplinary conference provided an interactive platform for exchanging ideas through a program of lectures, poster presentations, breakout sessions and workshops. Three working groups met to plan consensus statements. Progress with BEAT-PCD projects was shared and new collaborations were fostered. In this report, we summarize the meeting, highlighting developments made during the meeting.Electronic supplementary materialThe online version of this article (10.1186/s12919-018-0098-9) contains supplementary material, which is available to authorized users.

Infectious myositis is rather uncommon. When caused by anaerobic organisms, myositis is usually polymicrobial. Trauma, ischemia, or a contiguous focus of infection is often an antecedent of myositis. We report a case of monomicrobial veillonella myositis in an immunocompromised patient. The infection responded to debridement and therapy with metronidazole.

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