Abstract:The current report describes the development of a dual modality tomographic agent for both positron emission tomography and magnetic resonance imaging (PET/MRI). The dual-modality agent in this study was based on a 124 I (PET) radiolabeled tri-gadolinium endohedral metallofullerene Gd 3 N@C 80 (MRI) nanoprobe platform. The outer surface of the fullerene cage of the Gd 3 N@C 80 metallofullerenes was surface functionalized with carboxyl and hydroxyl groups (f-Gd 3 N@C 80 ) using previously developed procedures and subsequently iodinated with I-f-Gd 3 N@C 80 , which could ultimately be used for simultaneous PET/MR imaging.

Abstract:The performance of passively mode-locked Nd:GYSGG lasers was investigated for the first time. The 1061.5 nm continuous wave (CW) mode-locking operation of the Nd:GYSGG crystal was achieved and pulse as short as 3.1 ps have been generated with a semiconductor saturable absorber mirror (SESAM). At the pump power of 7.39 W, the maximum average output power of 1.27 W was obtained with the slope efficiency of 18.9%. The pulse repetition rate of 42 MHz was obtained.Intensity, ×10 4 a.u.

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We demonstrate a comparative investigation on Er,Pr:GYSGG and GYSGG/Er,Pr:GYSGG composite crystals at 2.79 μm. Simulating results show the highest temperatures are 369 K and 318 K, respectively. A maximum output power of 825 mW with slope efficiency of 19.2% and maximum laser energy of 3.65 mJ with slope efficiency of 22.7% are obtained in the GYSGG/Er,Pr:GYSGG composite crystal, which have an obvious improvement than those of Er,Pr:GYSGG crystal. The thermal focal lengths are respectively 41 and 62 mm when the pump power is 2.5 W. All these results indicate that the GYSGG/Er,Pr:GYSGG composite crystal has great advantages in reducing the influence of thermal effects and improving laser performances.

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