Goblet cell carcinoids are uncommon but distinctive tumours of the appendix. We have reviewed 11 cases diagnosed within the period 1976-1990. The mean age at presentation was 58 years (range 24-76), with a female:male ratio of 8:3. At presentation, in seven patients tumour was confined to the appendix or mesoappendix (mean age 51) and in four there was extension beyond the appendix (mean age 69). Of the seven patients with localized tumour, six are alive and without clinical disease after a mean follow-up period of 32 months and one died with recurrent tumour after 10 years. Of the four with more extensive disease, two died during follow-up (at 23 months with probable liver metastases and at 16 months with intestinal obstruction) and two are alive, one with disease and one clinically disease-free. Immunohistochemistry showed that all of the tumours stained positively for either neuron-specific enolase, chromogranin A or protein gene product 9.5. No tumour stained with antiserum to substance P and none showed glucagon-like immunoreactivity, but four cases stained positively for pancreatic polypeptide, an unusual feature in midgut carcinoids.
Chronic lymphocytic leukaemia (CLL) infiltrating the skin is uncommon and can present in different forms. We report a case of CLL infiltrating the prominent parts of the face and the scalp. A 63-year-old male with a 10-year history of CLL presented with plum-coloured swelling of the skin of the ears, eyebrows, tip of the nose and the scalp. Histopathology showed dense sheets of lymphoid infiltrate of the dermis which stained positive with B-cell markers CD20 and CD5 in keeping with the infiltrate of CLL.
British research on social movements, with a few exceptions, has been criticised for making little reference to social movement theory, such that the term, social movement is often used as an unproblematic descriptor. This failure leaves intact assumptions about the relationship between the aims, organisation and activity of social movements and the `interests' that underlie them. This paper attempts to integrate theoretical and substantive analyses of social movements in the context of the `two women's movements' in the United States and Britain which have had the family as a key focus for mobilisation: one conventionally associated with feminism, the other a mass movement of women mobilised to challenge feminism's claim to speak on their behalf. The analysis reveals the limitations of both mainstream and radical/Marxist explanations of social movements on account of their shared reductionist orientation. It suggests that a more fruitful account is provided by resource mobilisation and post-Marxist theorists who, despite drawing on different traditions and questions, recognise the autonomy of politicised culture. The article concludes by questioning whether any foundationalist notion of `interests' and the associated concept of `identity' can provide the basis for grounding political behaviour.
Two cases of basal cell carcinoma (BCC) occurring in association with long-standing dermatofibroma are reported. These lesions were asymptomatic, but both were characterized clinically by central ulceration. Histopathology of both cases revealed a BCC overlying a typical dermatofibroma. The association of these two tumours has rarely been reported and is controversial. It is disputed whether the changes of BCC overlying dermatofibromata are reactive or neoplastic.
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