Selecting an appropriate therapy for osteonecrosis of the jaws management based on current literature is a rational decision that can help lead to a proper treatment plan.
Background:Osteoradionecrosis of the jaw (ORNJ) is the most severe and complex sequel of head and neck radiotherapy (RT) because of the bone involved, it may cause pain, paresthesia, foul odor, fistulae with suppuration, need for extra oral communication and pathological fracture. We treated twenty lesions of ORNJ using low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT). The objective of this study was to stimulate the affected area to homeostasis and to promote the healing of the oral mucosa.Methods:We performed aPDT on the exposed bone, while LLLT was performed around the bone exposure (red spectrum) and on the affected jaw (infrared spectrum). Monitoring and clinical intervention occurred weekly or biweekly for 2 years.Results:100% of the sample presented clinical improvement, and 80% presented complete covering of the bone exposure by intact oral mucosa.Conclusion:LLLT and aPDT showed positive results as an adjuvant therapy to treat ORNJ.
Medication-related osteonecrosis of the jaws (MRONJ) can be considered an inability of the alveolar bone to respond to an injury, which frequently leads to severe local and systemic complications. Once the problem is installed, dentist must use all therapeutic approaches recommended. This manuscript reports a successful management of MRONJ handled with antibiotics, conservative debridement, low-level laser therapy (LLLT), and photodynamic therapy (PDT) up to 12 months. As healing of MRONJ may be very slow, combined therapeutic approaches are required. Besides the recommended conventional treatment protocol, LLLT and PDT are important tools to contribute to healing and improvement of patient's quality of life.
Aims:
This study aimed to improve malnutrition in mice and elderlies with a new dairy/buriti oral dietary supplement.
Background: Malnutrition is a prevalent problem in the elderly; therefore, oral dietary supplementation is an important strategy to reduce the incidence of this health problem.
Objective:
The present study evaluated the effects of a low-cost food supplement, made from by-products of the dairy and fruit industry in the Brazilian Cerrado (Buriti), on the nutritional status and the recovery of the metabolic profile of malnourished animals and elderly women.
Methods:
In the pre-clinical phase, Swiss mice were divided into six groups and subjected to malnutrition and renutrition. The clinical phase was carried out with 25 elderly women residing at a long-term institution, aged ≥ 65 years and with malnutrition or risk of malnutrition.
Results:
The analyzes showed improvements in anthropometric parameters and an increase in serum albumin levels, in addition to lipid profile improvement in the preclinical phase and an increase in the red blood cells and hemoglobin in the clinical phase.
Conclusion:
The supplement based on buriti was able to reverse malnutrition promoting improvements in anthropometric and biochemical parameters.
Used as the base for the study a sample of ratings of 15 pilots made by supervisors during a 6-month period. This report of that evaluation confirms the validity of technique (Smith, 1974) using intraclass correlation and Spearman's rho to identify which rates were unreliable. More rigorous criteria for the elimination of unreliable raters were developed by applying the Kuder-Richardson reliability than the intraclass correlation criteria used by Smith. The proposed technique permits improved reliability by the criterious removal of the raters who are not contributing significantly to the total consistency of the behavioral scale and thus eliminates partially the inconvenience of the unavailable significant table of data to test the acceptance of the reliability.
Resumo O ano de 2016 marcou uma signiĄcativa mudança de paradigma associada ao comportamento das botnets. Ao infectar dispositivos computacionais não convencionais como câmeras e roteadores domésticos, o malware Mirai propiciou um aumento, não somente na abrangência, mas também na capacidade de ataques das botnets. Este fato enfatiza a importância de desenvolver novos métodos para detectar botnets. Um deles envolve o uso de algoritmos de mineração de fluxos contínuos para classiĄcar tráfego malicioso em uma rede. Embora já existam algumas iniciativas que adotem essa abordagem para detectar botnets, vários problemas de pesquisa ainda estão abertos. Um ponto importante está relacionado ao alto custo e grande esforço dispendido pelos proĄssionais de segurança para obter dados rotulados. Sendo assim, o principal objetivo deste trabalho abrange a avaliação do uso de algoritmos de mineração de fluxos contínuos de dados para a detecção de botnets considerando requisitos mais próximos aos cenários reais, tais como: i) os fluxos de dados estão constantemente chegando, ii) novos ataques podem surgir e tais ataques não estão presentes no modelo de decisão, iii) poucos fluxos são rotulados e iv) a avaliação da qualidade do classiĄcador deve ser feita atentando-se para o momento em que os fluxos chegam, em particular aqueles em que novos ataques chegam. Ao longo do trabalho, uma série de experimentos foi conduzido usando conjuntos de dados contendo tráfego real de diferentes tipos de botnets. Os resultados experimentais mostram o potencial da classiĄcação de fluxos contínuos de dados para detecção de botnets e revelam que é possível minimizar a quantidade de instâncias rotuladas apresentadas ao classiĄcador, mantendo um bom desempenho. Palavras-chave: Segurança da informação. Sistemas de detecção de intrusão. Botnets. ClassiĄcação de fluxos contínuos de dados.
Theories of personality, in their different proposition formulate levels of actuation that range from the associative system (S‐R pattern) to the S's level of significance (S‐S pattern), going through the mediating processes (S‐0‐R pattern). Such divergence of points of view suggested a necessary bridge to link the different patterns and establish a connection from the nucleus to the periphery. This was accomplished by an image of the personality symbolized in a sphere that represents an indivisible concept. The multiplicity of dimensions that characterize man—seen as an indivisible and univocal whole—are represented by the multiple interaction of three worlds: The umwelt, the mitwelt and the eigenwelt, within the sphere of personality.
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