Development and Evaluation of a Low-cost Dairy Food Supplement with Mauritia Flexuosa (Buriti) to Combat Malnutrition: Translational Study in Mice and Institutionalized Elderly Woman

Abstract

Aims: This study aimed to improve malnutrition in mice and elderlies with a new dairy/buriti oral dietary supplement. Background: Malnutrition is a prevalent problem in the elderly; therefore, oral dietary supplementation is an important strategy to reduce the incidence of this health problem. Objective: The present study evaluated the effects of a low-cost food supplement, made from by-products of the dairy and fruit industry in the Brazilian Cerrado (Buriti), on the nutritional status and the recovery of the metabolic profile of malnourished animals and elderly women. Methods: In the pre-clinical phase, Swiss mice were divided into six groups and subjected to malnutrition and renutrition. The clinical phase was carried out with 25 elderly women residing at a long-term institution, aged ≥ 65 years and with malnutrition or risk of malnutrition. Results: The analyzes showed improvements in anthropometric parameters and an increase in serum albumin levels, in addition to lipid profile improvement in the preclinical phase and an increase in the red blood cells and hemoglobin in the clinical phase. Conclusion: The supplement based on buriti was able to reverse malnutrition promoting improvements in anthropometric and biochemical parameters.

Análise in vitro da atividade antioxidante e determinação do FPS de formulações dermocosméticas contendo óleo de buriti (Mauritia flexuosa L.)

“…Dentre as plantas da diversidade brasileira que podem ser utilizadas na produção de cosméticos, o buriti (Mauritia flexuosa) é uma das espécies encontradas no bioma Amazônico e Cerrado. Deste fruto é possível extrair um óleo vermelho-alaranjado, com características organolépticas de sabor e aroma agradáveis, qualificado por um alto teor de carotenoides, o que permite um variado número de aplicações para a indústria de produtos alimentícios, farmacêuticos e cosméticos (Bicalho et al, 2021;Marcelino et al, 2022;Morais et al, 2022).…”