Geranium homeanum Turez is a herbaceous plant used as an empirical medicine. This research was carried out to test the antibacterial activity and determine minimum inhibition concentration (MIC) to Staphylococcus aureus and Pseudomonas aeruginosa with agar diffution method and phytochemical analysis of geranium leaves by Harbone method. The young and old geranium leaves were blended then filtrated. The obtained filtrate was divided into two parts, one part heated by autoclave and the other was unheated. Each filtrate was tested against to Staphylococcus aureus and Pseudomonas aeruginosa. Geranium leaves filtrate having the highest antibacterial activity was heated at 500C until it become dry powder. The powder was used to measure MIC and phytochemical analysis.The results showed that the antibacterial activity of young leaves filtrate was higher than the old leaves filtrat, and the unheated leaves filtrate was higher than heated filtrate one. MIC of S. aureus and P. aeruginosa, were as follows 15 mg/ml and 20 mg/mL respectively. The antibacterial activity of powder geranium’s leaves filtrate was weaker than 100 µg/mL ampicilline. Phytochemical analysis of geranium leaves showed positive contents of alkaloid and triterpenoid.
Soil fertility is the relationship between the physical, chemical and biological properties needed by plants to grow and develop. The land used as a medium for growing mustard greens is taken from Bahway Village. The soil is treated with organic and inorganic fertilizers to test its fertility. The data analysis used was one way ANOVA and the least significant difference test and a randomized block design with three treatments and two replications. The treatments were: P1=100% organic fertilizer, P2=100% inorganic fertilizer, P3=50% organic fertilizer + 50% inorganic fertilizer and control. Based on the research results, it is known that the type of soil texture in P1 and P2 has a clay-sand texture, while P3 and C have a sandy loam texture. In terms of chemical properties, the pH at P1, P2, P3 and C are 5.53, 5.79, 5.50 and 6.20. For available P values, P1 = 188.31 ppm, P2 = 7.44 ppm, P3 = 113.62 ppm, and C = 2.48. Availability of Cation Exchange Capacity P1 = 22.56me/100g, P2 = 21.80me/100g, P3 = 23.19me/100g, and C = 23.75me/100g. From these results, what showed that the growth of mustard plants increased was the P3 treatment.
Kemangi (Ocimum sanctum) is commonly used as a vegetable (fresh vegetables) and traditional medicine in Indonesia. Kemangi leaves have been empirically used as an alternative medicine for wound healing. Apart from kemangi, a morphologically similar plant to kemangi, namely ruku ruku, is often used by Indonesians as a cooking spice. The leaves of ruku ruku (Ocimum tenuiflorum) have been empirically used in various alternative medicine, namely to treat fever, cough, gout, nerves, mouth sores, tinea versicolor, nausea and vomiting. The research was conducted to determine the antimicrobial activity (antibacterial and antifungal), antioxidants and phytochemical analysis of the ethanol extract of kemangi leaves and ruku ruku leaves. The extraction method used is the maceration method using 96% ethanol as a solvent. The antimicrobial test was carried out using the agar diffusion method. The bacteria used are Salmonella typhi, Staphylococcus aureus, while the fungi used are Candida albicans. Phytochemical analysis used the Harbone method, and the antioxidant test used the 1,1-Diphenyl-2-picryl Hidrazil (DPPH) method. The results showed that the extracts of kemangi and ruku ruku leaves contained flavonoid and steroid compounds. The antimicrobial test results showed that only ruku ruku leaves inhibited the growth of Staphylococcus aureus with an inhibition zone of 9.35 mm, and the two extracts used could not inhibit the growth of the fungus Candida albicans. In contrast, the results of the antioxidant test showed that the ruku ruku and kemangi leaf extracts had an antioxidant activity with inhibition concentration 50 (IC50) values of 225.64 ppm and 455.11 ppm. Keywords: Bioactivity, Kemangi, Phytochemicals, Ruku.
Traditionally, Senna Alata (L.) Roxb (Ketepeng Cina) has been used as an alternative medicine for typhus, diabetes, malaria, herpes, eczema, asthma, stomach ulcers, syphilis, influenza, bronchitis, intestinal worms, fungal skin diseases such as tinea versicolor, ringworm and scabies. The study's objective was to determine the active compounds, antioxidant potency and antifungal activity of Senna Alata (L.) Roxb leaves extract. Samples were extracted using the maceration method with 70% ethanol, ethyl acetate and N-hexane as solvents. Phytochemical analysis used the Harbone method, antioxidant testing using 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and antifungal testing using the agar diffusion method. Phytochemical results proved that all Senna Alata (L.) Roxb leaves extract contained alkaloids, saponins, tannins, flavonoids, triterpenoids, steroids, glycosides. While the antioxidant test stated that ethanol and ethyl acetate solvents had solid antioxidant potential with the Inhibition Concentration (IC50) values obtained were 66.01 ppm and 78.23 ppm respectively. While the solvent N-hexane has a moderate antioxidant potential, the IC50 value obtained is 138.80 ppm. The diameter inhibition zones of ethanol, ethyl acetate, and N-hexane extracts against the Candida albicans were 8.66 mm, 10.22 mm and 8.84 mm, respectively. Cryptococcus neoformans was only inhibited by ethyl acetate and N-hexane Senna Alata (L.) Roxb leaves extracts with diameter inhibition zones of 4.84 mm and 4.44 mm, respectively. Key words: Antifungal, Antioxidant, Candida albicans, Cryptococcus neoformans, Phytochemical , Senna alata (L.) Roxb.
Abstrak Pertumbuhan merupakan suatu peningkatan ukuran fisik tubuh yang ditunjukkan dengan terjadinya penambahan jumlah dan volume sel baik secara keseluruhan atau sebagian yang dapat diukur. Banyak faktor yang mempengaruhi pertumbuhan tubuh, salah satunya adalah faktor lingkungan. Faktor lingkungan yang paling umum dan dapat dimodifikasi adalah makanan. Makanan sebagai sumber nutrisi dan zat pembangun di dalam tubuh. Nutrisi yang tidak seimbang dapat menyebabkan berbagai masalah kesehatan. Oleh karena itu pengabdian kepada masyarakat (PkM) yang dilakukan bertujuan untuk mengetahui status gizi dari pertumbuhan para siswa Sekolah Dasar (SD) “X” dan ‘Y” di Indramayu dalam rangkaian kegiatan PkM Fakultas Kedokteran-Universitas Kristen Indonesia di Desa Eretan Wetan, Kandanghaur-Indramayu pada tanggal 22 Februari 2020. Metode yang digunakan adalah metode antropometri yaitu pengukuran berat badan dan tinggi badan, kemudian dari hasil kedua pengukuran tersebut dihitung nilai Indeks Massa Tubuh (IMT). Berdasarkan nilai IMT yang diperoleh diketahui bahwa dari 245 siswa ditemukan 60 siswa (24.5%) memiliki status gizi yang bermasalah yaitu mengalami kekurusan dan kegemukan. Pada siswa yang mengalami status gizi yang bermasalah, diketahui sebanyak 46 siswa (76.6%) tergolong kurus dan 14 siswa (23.3%) tergolong gemuk. Oleh karena itu maka perlu dilakukan identifikasi jenis dan ragam makanan yang dikomsumsi oleh siswa SD “X” dan “Y” di Indramayu tersebut, sehingga dapat dilakukan upaya edukasi yang tepat tentang pentingnya mengkonsumsi makanan gizi seimbang pada anak usia sekolah. Kata Kunci: Antropometri; Pertumbuhan
Aims: Due to the complexity of teaching new subjects to medical freshmen, especially in basic medical science, and the variability of the academic performance, we want to explore the difference of our student’s Biochemistry examination score based on their gender and place of residence. Methods: This is a simple retrospective cross sectional study by analyzing the examination result and compared it based on our student’s gender (male or female) and place of residence (living in their own house or in boarding house). Result and Discussion: During data collection, there are 913 active students from all class of 2016-2021 but only 569 freshmen from the class of 2018-2021 which gender and place of residence data are available, there are 155 male (27.24%) and 414 female (72.75%). Female students achieved better mean score compared to their male counterparts. Students which live in their own house also achieved better mean score compared to those who lived in boarding house. Conclusion: there are differences in the achievement of examination scores based on student’s gender and place of residence.
Kabau (Archidendron bubalinum) is one of the plants that is often used as food ingredients and has the potential to be developed in the health sector. This study aims to determine the antioxidant potential of kabau seeds using 2,2-diphenyl-1-picril hidrazil (DPPH) and ferric reducing ability power (FRAP) methods and to identify active compounds of kabau seeds using GC-MS. Kabau seeds were macerated using 70% ethanol and 99.9% ethanol. The results showed that 99.9% ethanol extract of kabau seed coat had the highest antioxidant activity with IC50 values of 26.75 ppm for the DPPH method and 121.55 ppm for the FRAP method, respectively. Identification of active compounds using GC-MS showed that 99.9% ethanol extract of kabau seed coat contained the most 9,12-octadecadienoic acid compounds (linoleic acid) so that it could be developed as an antioxidant.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.