in coronary occlusion and suggested the possibility that the disturbance in the cardiac mechanism may be due to myocardial anoxemia. In man deLavergne and his associates19 noted a transitory Stokes-Adams syndrome with brachycardia eight days after the injection of antistreptococcus serum for erysipelas, at which time serum sickness developed. Also, Harkavy20 observed certain cardiac arrythmias and angina pectoris in 3 patients when offended by certain allergens. The relation of the changes in the electrocardiograms to the anaphylactic shock in our case is conjectured. Nevertheless, there were abnormally broad P waves and flat Ts shortly after the shock which returned to normal later. SUMMARY A man aged 22 had severe anaphylactic shock two hours after an injection of tetanus antitoxin. The patient was gravely ill and laboratory examinations showed hemoconcentration with a red blood count of 6,910,000. On this basis, he was given 2,000 cc. of physiologic solution of sodium chloride intravenously during a period of two hours, which resulted in dramatic improvement with recovery. The red blood cell count dropped to 5,700,000 at the end of this therapy, to 5,000,000 within six hours and to 4,610,000 within twelve hours of administration of saline solution.
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