Filariasis is a chronic infectious disease, caused by filarial worms in the lymph and lymph nodes cause lymphangitis and elephantiasis. Batuah Village is the area in Sampit with the largest percentage of microfilariae compared to the surrounding area. From 196 the number of Batuah villagers examined by the filariasis elimination officer of Kotawaringin Timur District Health Office in 2013 obtained 5 positive cases of filariasis with 2.55% microfilaria number which is dominated by filaria worm Brugia malayi. From the local health center has also conducted a mass drug treatment program with DEC medication, combined with albendazole for 12 days on 14-16 July 2014. The aim of this study was to determine the success rate of treatment conducted by the health officer against filariasis patients in the Batuah village. The method used in this microfilariae examination is a microscopic method. Capillary blood was taken on 4 filarial patients who tested positive on the previous examination who had been given DEC + Albendazole treatment, the result from 4 samples that examined 1 positive sample of 4 patients. The implementation of medication that has been done by public health office was successful because there was a decrease of microfilaria rate which was previously 2.55% to 0,51% (<1%).
Diabetes mellitus is a disease characterized by hyperglycemia or an increase in blood glucose levels. The state of hyperglycemia is one of the supporting factors for oral candidiasis infection. The purpose of this study was to determine the correlation of hyperglycemia with the incidence of Candida albicans infection in patients with Diabetes mellitus. this study was conducted on 30 respondents. Blood glucose levels and Candida albicans culture were measured using the germ tube test method. Data analysis to see the correlation using the Chi-Square test obtained Sig. (0.015 0.00.050) and it can be stated there is a correlation between variables. From the results of data analysis, it can be concluded that there is a correlation between hyperglycemia and Candida albicans infection which causes oral candidiasis in DM patients.
Lumbricus rubellus earthworm is known having antioxidant and antibacterial properties such as Polyphenolic, Glycoprotein G-90, and Lumbricin I. These substances also work as hepatoprotective agents in the parenchymal cell damage due to infection. This study aims to determine the antioxidant properties of earthworm extract (Lumbricus rubellus) in reducing the levels of ALT, AST, and a number of the bacterial colony in male Wistar rats infected by Salmonella thypimurium as a model of S.typhii infection. Posttest-only control group design method was carried out in 28 samples which divided into 4 treatment groups. The blood samples were taken for the ALT and AST measurement on day 18. The bacterial colony measurement was conducted by growing the bacteria in the feces with Total Plate Count (TPC) method. The ALT levels in T2 were significantly decreased (P<0.05; 25.9 ± 5.50 U/L), followed by T1 (P<0.05; 35.6 ± 1.46 U/L). The AST levels in the T2 and T1 groups were also significantly decreased (P<0.05; 81.4 ± 13.44 U/L and 107.8 ± 9.45 U/L respectively). The bacterial colony of S.thypimurium was also significantly decreased in the T2 and T1 with the mean of 6.89 ± 2.06 x 10-1 and 8.38 ± 2.15 x 10-1 respectively. The Kruskal-Wallis test found a significant difference between variable groups (P < 0.05), but the Mann-Whitney test showed no significant difference only between T1 and T2 group for the bacterial colonies (P = 0.180). The Lumbricus rubellus extract have a hepatoprotective and antibacterial properties by significantly reduce the levels of amino transaminase enzyme (ALT and AST) and bacterial colonies of S.thypimurium in male Wistar rats.
Severe Acute Respiratory Sindrome Coronavirus 2 (SARS-Cov-2) adalah virus dari Ordo Nidovirales family Coronaviridae yang menyebabkan sindrom pernafasan akut pada manusia. Virus ini pertama kali ditemukan kasusnya di Kota Wuhan, China pada medio Desember tahun 2019 dan ditetapkan oleh WHO sebagai Pandemi Global. Tata laksana penanganan pasien menjadi hal krusial dalam menekan angka mortalitas pasien dengan COVID-19 positif. Infeksi virus sebenanrya adalah self-limited disease dengan pengobatan bersifat suportif. Support pengobatan yang baik memerlukan informasi dan kejelasan pathogenesis virus, hasil laboratorium, gejala klinik pasien dan analisa mendalam mengenai karakteristik virus dan respon imun tubuh terhadap infeksi
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