Our finding indicates that different test extracts were able to ameliorate the derangements in lipid metabolism caused by diabetes mellitus in alloxan induced diabetic rats towards normal level.
All findings suggest that the antifertility activity of extract could possibly be through the changes in the implantation site, altered hormonal levels, prolonged estrous cycle and anti-estrogenic activity. Hence, the extract possesses reversible antifertility activity without adverse toxicity in female rats.
Amaranthus spinosus Linn. (Amaranthaceae) is found throughout India. This tree species has been of interest to researchers because it is a medicinal plant employed in the Indian traditional system of medicine. Pharmacognostic standardization; physico-and phytochemical evaluation of the roots of Amaranthus spinosus was carried out, to determine its macro-and microscopical characters, and also some of its quantitative standards. Microscopical studies were done by using the trinocular microscope. Total ash, water-soluble ash, acid-insoluble ash, sulfated ash values, and alcohol-and water-soluble extractive values were determined for physico-chemical evaluations. A preliminary phytochemical screening was also done to detect different phytoconstituents. Microscopically, the root showed cork, cortex, stellar region, and calcium oxalate crystals. Powder microscopy showed anamalous secondary growth in between the xylem vessels and Calcium Oxalate crystals in the cortex region. Total ash was approximately three times more than acid insoluble and water soluble ash. The ethanol soluble extractive was approximately the same as the water soluble extractive. Thin Layer Chromatography (TLC) of the Petroleum-ether extract using Benzene : Ethyl acetate (6 : 1), showed six spots. In the chloroform extract, using Benzene : Ethyl acetate (4 : 1) nine spots were seen, and in the ethanol extract, using Chloroform: Methanol (93 : 7), only four spots were observed, using Iodine vapor as a viewing medium. Phytochemically, the root exhibited terpenes, alkaloids, glycosides, and sugars. These findings might be useful to supplement information with regard to its identification parameters, which are assumed significant in the way of acceptability of herbal drugs, in the present scenario, which lacks regulatory laws to control the quality of herbal drugs.
Acacia leucophloea (Mimosoideae) is native to Southeastern Asia. This tree species has been of interest to researchers because it is a medicinal plant employed in the Indian indigenous system of medicine. Pharmacognostic standardization, physico-chemical evaluation of the roots of Acacia leucophloea was carried out to determine its macro-and micro-scopical characters and also some of its quantitative standards. Microscopical studies were done by using trinocular microscope. Total ash, water-soluble ash, acidinsoluble ash and sulphated ash values, alcohol-and water-soluble extractive values were determined for phytochemical evaluations. Preliminary phytochemical screening was also done to detect different phytoconstituents. Microscopically, root showed cork, cortex, stellar region and calcium oxalate crystals. Powder microscopy showed crystal fibres, xylem fibres in bundle, phloem fibres, medullary ray, and cork cells, parenchyma cells with red cell content, tissues with abundant xylem vessels with pitted thickenings, parenchyma, and Stone cells. Total ash was approximately two times and four times more than acid insoluble and water soluble ash, respectively. Ethanol soluble extractive was approximately two times higher than water soluble extractive. TLC of petroleum ether and chloroform extract showed nine spots using benzene:methanol (19:1) and chloroform:methanol (19:1) respectively while ethanol extract showed four spots using ethyl acetate. Phytochemically, root exhibited alkaloids, terpenes, flavanoids and tannins.
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