Background:The "ABO" blood group system is associated with some diseases including gastric and duodenal ulcer, hepatitis B1, vascular diseases, abdominal aortic aneurism, and cancers. Some epidemiological studies demonstrated the linkage among the "ABO" blood group and the risk of type 2 diabetes mellitus (DM). Aims and Objective -This study aimed to find out the possible linkage between "ABO" and "Rhesus" blood groups with type 2 DM. Material and Methods: This study was carried out in Department of Physiology, Muzaffarnagar Medical College and Hospital, Muzaffarnagar from April 2017 to June 2017. This study included total 1316 individuals in which 104 were diabetic patients, and 1212 individuals were non-diabetic apparently healthy controls. Diabetic patients were taken from diabetic outpatient clinics, and the controls were taken from healthy individuals coming for blood donation at blood bank of Muzaffarnagar Medical College and Hospital, Muzaffarnagar. Standard slide agglutination test for the determination of ABO and Rh blood groups was used. Data thus obtained were analyzed by applying Chi-square test to determine any association between DM and different ABO and Rh blood groups. Data were expressed as percent and absolute number of frequency. Results: Increased frequency of blood group AB and blood group O (18.26% vs. 10.31%, 34.61% vs. 29.31%) were found in diabetes. On applying Chi-square test, statistically significant association was found between blood groups AB and O and DM (Chi-square value -8.24, P < 0.04). Increased frequency of Rh positive blood group in diabetic (96.15% vs. 95.54%) but association between Rh blood group and diabetes was not statistically significant. (Chi-square value -0.021, P = 0.88). Conclusion: Blood group might be a risk factor and it can be helpful for the evaluation of the disease.

Background: Obesity is a newer chronic non-communicable disease, one of the today's most neglected public health problems according to WHO. While the complication of obesity such as diabetes, cardiovascular disease, and osteoarthritis are well established, but less emphasis is traditionally placed on the effects of obesity on the respiratory system. Aims and Objective: To study the effect of gender and correlation of body mass index (BMI) with pulmonary function tests (PFTs). Materials and Methods: This study was done on 115 first year Medical and Paramedical Students of Muzaffarnagar Medical College, Muzaffarnagar. Following the selection, the participants were divided into two groups based on BMI < 25 and BMI > 25. Anthropomeric parameters and spirometeric parameters were measured using a computerized spirometer. Statistical analysis was done by applying Student's t-test. Linear association was established using Pearson's correlation. Results: On comparing the female participants with male participants, PFTs (forced vital capacity [FVC], forced expired volume in 1 second [FEV1], FEV1/FVC, peak expiratory flow rate) were found to be significantly lower in female than male. On observing, the correlation of pulmonary function parameter with BMI correlated positively with BMI < 25. PFTs were negatively correlated with increasing BMI in both male and female participants but the correlation is not statistically significant. Conclusion: Our finding suggests that there is a significant impairment of lung functions in the overweight individuals.

Background: Benzene exposure is one of the main health concerns for high risk occupations like petrol pump workers. But there is little knowledge about the effect of benzene metabolites on blood parameters. Aims & Objective: The objective of this study is to find out the effect of benzene exposure on hematological parameter especially eosinophil count on petrol pumps workers. Materials and Methods: Fifty four (54) petrol pump workers between age group of 20-60 years were included in this study and categorized into 04 groups according to duration of exposure. The data collected are represented as mean ± SD. These changes were statistically significant (<0.05) when we compared eosinophil count in study group and control group, when duration of exposure is less than 10 years. Results: When we compared eosinophil count in subjects exposed to more than 15 years the count was significantly (<0.05) decreases. The count decreases as the duration of exposure increases. Conclusion: Long term exposure to benzene may cause bone marrow suppression leads to decreased eosinophil count.

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