Over the last decade the discourse of responsible innovation (RI) has become a significant feature of debates concerning the relationships between science, innovation and society in the fields of biosciences and biotechnologies. We document how this discourse has evolved over the period 2014-2019 at a Synthetic Biology Research Centre hosted within a University in the UK (BrisSynBio). We describe how an approach to RI has evolved to include but go beyond public engagement, by encouraging practices aimed at anticipation, reflexivity and deliberation in sometimes creative and innovative ways. We describe how the Centre has struggled to capture the impacts of RI interventions on the everyday practices and behaviours of scientists and the outcomes of their work. The study reveals the importance of leadership, creativity, innovation, institutional support, openness to change and mechanisms of capturing impact for successful RI institutionalisation.
It is increasingly suggested that shortages in the supply chain for human blood could be met by the development of techniques to manufacture human blood ex vivo. These techniques fall broadly under the umbrella of synthetic biology. We examine the biopolitical context surrounding the ex vivo culture of red blood cells through the linked concepts of alienation, immunity, bio-value and biosecuritization. We engage with diverse meanings of synthetic blood, and questions about how the discourses of biosecurity and privatization of risk are linked to claims that the technology will address unmet needs and promote social justice. Through our discussion we contrast communitarian ideas that culturing red blood cells 'extends the gift' of adult blood donation with understandings of the immunitary logics that underpin the cord-blood economy.
There is a growing recognition within cognitive enhancement and neuroethics debates of the need for greater emphasis on cognitive artefacts. This paper aims to contribute to this broadening and expansion of the cognitive-enhancement and neuroethics debates by focusing on a particular form of relation or coupling between humans and cognitive artefacts: interaction-dominance. We argue that interaction-dominance as an emergent property of some human-cognitive artefact relations has important implications for understanding the attribution and distribution of causal and other forms of responsibility as well as agency relating to the actions of human-cognitive artefact couplings. Interaction-dominance is both indicated and constituted by the phenomenon of “pink noise”. Understanding the role of noise in this regard will establish a necessary theoretical groundwork for approaching the ethical and political dimensions of relations between human cognition and digital cognitive artefacts. We argue that pink noise in this context plays a salient role in the practical, ethical, and political evaluation of coupling relations between humans and cognitive artefacts, and subsequently in the responsible innovation of cognitive artefacts and human-artefact interfaces.
The idea of "style" emerges at several important points throughout Husserl's oeuvre: in the second part of the Crisis of the European Sciences, the lectures on intersubjectivity published in Husserliana XV, and in the analyses of transcendental character and intersubjectivity in the second book of the Ideas. This paper argues that the idea of style, often overlooked, is in fact central to understanding Husserl's conception of the person and intersubjective relations, its role in the latter captured in his odd turn of phrase, "intuitive flair." Moreover, by showing the interdependence between the ideas of style and institution (Stiftung), I argue that institution also has a central role in Husserl's account of constitution and personhood. The relevance of the relation between institution and style goes beyond Husserlian phenomenology. In his late writings, Merleau-Ponty makes this relation the centerpiece of his attempts at an "indirect-ontology." Thus the investigation of Husserl's concept of style that I carry out here becomes an important propaedeutic for the study of style that Merleau-Ponty calls for in his later work. In brief, the concept of style has an important role to play in any phenomenological account of personhood and intersubjective relations.
Finding avenues for collaboration and engagement between the arts and the sciences (natural and social) was a central theme of investigation for the Responsible Research and Innovation (RRI) and Public Engagement programme at BrisSynBio, a BBSRC/ EPSRC Synthetic Biology Research Centre that is now part of the Bristol BioDesign Institute at University of Bristol (UK). The reflections and experiments that appear in this dossier are a sample of these investigations and are contributed by Maria Fannin, Katy Connor and David Roden. Darian Meacham coordinated and introduces the dossier.
and Nature: Examining the Relationship between Phenomenology and Naturalism', points to a problem that, like many fundamental problems in philosophy, is at once strikingly contemporary and classical: how can we account for the place of human experience in nature when the special sciences that have emerged from experience to study nature seem unable to situate it? Questions about the relationship between consciousness and the natural world have been at the centre of many philosophical debates: how can we relate first-and third-person data? Is it possible to explain exhaustively, or at all, consciousness in naturalistic terms? Although these questions have been the driving force of much recent philosophical work, one issue in particular has been underexplored within this broad field: what is the relationship between phenomenology (as a philosophical method for describing lived experience) and the broadly accepted idea that philosophy should be consistent with a naturalistic worldview. Put otherwise, how does human thought think about a nature that by its own account precedes it; how can we think a world without thought? These are two sides of the same question. On the one hand, we ask: how do we think about experience or consciousness as located in nature? And on the other hand, how do we think about what exceeds or transcends thought, but does not exclude it (or rather contains it), namely nature? These questions have emerged in various registers and in different traditions throughout the history of philosophy and have taken on a particular poignancy with the rise of modern science and the naturalistic worldview that underpins it. But they all ultimately refer to a seemingly intractable ontological problem that has played a large role in the history of philosophy from the pre-Socratics to Kant and Heidegger: what is the
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