Abstract. The objective of this study was to compare the physicochemical profile of white and purple grape juices through the analysis of reports from the database of an oenological laboratory located in the Serra Gaúcha. The reports of the years 2012 through May of 2016 containing the parameters alcohol, pH, reducing sugars, relative density, titratable acidity, total soluble solids and volatile acidity were used for the statistical evaluation. There was no statistically significant difference regarding the alcohol content and density of white juices compared to purples in any year. Statistically significant pH values were found in the crops of 2014 and 2015. As for the reducing sugars parameter, it was observed a statistically significant difference in the year of 2014. Titratable acidity was statistically significant in all crops. Statistically significant values of total soluble solids were observed in the harvests of 2014 and 2015. The volatile acidity parameter showed statistical significance in the year 2014. The inherent genetic differences between the varieties of grapes used for each juice and the distinct technological processes used in the production are the factors that explain the results.
Oxytocin has been administered to patients with autism spectrum disorder (ASD) in order to improve social skills, communication, and manage repetitive behaviors in the context of research trials. The majority of the studies focus on acute administration; thus, the effectiveness and potential side effects of chronic administration remain unknown. The main goal of this case report is to highlight the importance of the safety parameters for the chronic use of intranasal oxytocin administration. In a single case conducted in our outpatient clinic, one adolescent (15 years old) received intranasal oxytocin (24 IU) twice per day, in accordance with the recommended doses for this age group that varies from 8 - 25 IU twice per day. After three weeks of treatment, the patient presented with gynecomastia. While it is not certain that the gynecomastia was oxytocin-induced, this case highlights the importance of developing optimal regimens for chronic oxytocin administration, with a particular focus on safety parameters.
Objective: To systematically review the scientific literature relating the effects of trans fatty acids on cardiovascular risk. Methods: A literature search was conducted in the following databases: MEDLINE, LILACS andScienceDirect in September of 2015. The following descriptors were used: Trans Fat AND Trans Fatty Acids AND Cardiovascular Diseases present in the title, keywords or MeSH Terms and abstract. The included studies were conducted in humans, published in Portuguese, English or Spanish. Studies were excluded for being case study reports, case-control or review articles. Results: There was a positive association between the consumption of trans fatty acids and deleterious changes in risk factors for cardiovascular disease. Conclusion: Given the importance of eating habits on health, it is relevant to note that reducing the trans fat content of foods and of the diet is only one component of a multifaceted strategy to improve nourishment and reduce the risk of chronic diseases related to diet, in particular cardiovascular diseases. Objetivo: Sistematicamente revisar a literatura científica, relacionando os efeitos dos ácidos graxos trans com o risco cardiovascular. Métodos: A busca bibliográfica foi feita nas seguintes bases de dados: MEDLINE,LILACS e ScienceDirect em setembro de 2015. Foram utilizados os seguintes descritores: Trans Fat AND Trans Fatty Acids AND Cardiovascular Diseases, presentes no título, palavras-chave ou MeSH Terms e resumo. Foram incluídos estudos conduzidos em humanos, publicados nos idiomas português, inglês ou espanhol. Foramexcluídos estudos que reportavam estudo de caso, caso-controle ou artigos de revisão. Resultados: Observouse uma associação positiva entre o consumo de ácidos graxos trans e mudanças desfavoráveis em fatores de risco para doenças cardiovasculares. Conclusão: Dada a importância dos hábitos alimentares sobre a saúde, é relevante observar que a redução do teor de gordura trans de alimentos e da dieta é apenas um componente de uma estratégia multifacetada para melhorar a alimentação e reduzir o risco de doenças crônicas relacionadas com a dieta, em particular doenças cardiovasculares.
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