Intracellular transport of sulfated macromolecules in parotid acinar cells was investigated by electron microscopic radioautography after injection of 35S-sulfate. Ten minutes after injection radiosulfate was concentrated in the Golgi region. By 1 hr, much of the radioactive material had been transported to condensing vacuoles. These vacuoles were subsequently transformed into zymogen granules which contained almost 70% of the radioactivity 4 hrs after injection. These results indicate that, in addition to its packaging function, the Golgi apparatus in parotid acinar cells is capable of utilizing inorganic sulfate for the production of sulfated macromolecules. These molecules, following an intracellular route similar to that taken by digestive enzymes, become an integral component of zymogen granules. The possibility that sulfated macromolecules play a role in exocrine secretion by aiding in the packaging of exportable proteins is discussed.
Both surfaces studied may be used at implant-abutment junctions and both possess an ability to establish a bacterial biofilm containing a periodontally-relevant species. These surfaces are thus able to facilitate the apical migration of bacteria associated with peri-implantitis.
Unifying the field of rehabilitation counseling appears to be a daunting task. Many researchers have investigated this phenomenon and have also written position papers arguing for a specific identity perspective: either as a counseling specialty or as a separate profession. The current study examined beliefs about the field of rehabilitation counseling among trainees and investigated factors that influenced these beliefs. A scale was developed to collect data about perceptions of master's-level students in Council on Rehabilitation Education (CORE)-accredited training programs. Data were collected from 67 participants in 12 programs. Results indicated that two-thirds of trainees believed that rehabilitation counseling is a counseling specialty. Previous work experience of the trainees was most likely to influence this position. Barnes et al.
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