The red blood cell (RBC) glutathione peroxidase (GSH-Px) activity and routine haematological parameters were measured in 38 healthy north Italian full-term pregnant women and in their newborn infants. In 31 pairs the serum selenium concentration was also measured. Data were compared with those of 20 normal adult controls (10 males and 10 females). Newborn infants exhibited significantly lower RBC GSH-Px activity and serum selenium concentrations than adult controls. Pregnant women had serum selenium values intermediate between those of adult female controls and their newborn infants. In both the pregnant women and newborns the RBC GSH-Px activity correlated with the level of selenium in serum which suggests that the neonatal RBC GSH-Px deficiency may be partially due to insufficient availability of selenium during pregancy. Factors other than selenium concentration, e.g. hormonal and genetic, might also affect the RBC GSH-Px activity as suggested by sex differences and mother/child concordances in enzyme activity found in our cases.
The half-life of Ti has been measured to be T&~2 --54.2+2. 1 yr, somewhat higher than previously published values of 46.4+1.7 and 48.2+0.9 yr. The present value was obtained from the specific activity and the radioisotope concentration of several TiOq samples, each spiked with a Ti activity of about 1.2 pCi. The specific activity was measured via the 1157 keV y line from the decay of the Sc daughter.Ti/Ti concentrations were measured with the Argonne FN tandem accelerator in conjunction with an Enge split-pole magnetic spectrograph using the technique of accelerator mass spectrometry. An overall sensitivity of 10 ' was achieved which proves accelerator mass spectroscopy to be a powerful tool for radioisotope detection also in a region of rather heavy ion masses. A detailed description of the subtleties of accelerator mass spectroscopy when applied to measure absolute radioisotope concentrations in this heavy mass region is presented. RADIOACTIVITY Measured half-life of Ti via accelerator mass spectroscopy.
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