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Aims: Recently, homocysteine has been noticed as the major pathogenesis factor of the cardiovascular diseases. The aim of the study was to investigate the effects of physical activities on the serum homocysteine levels, as well as other cardiovascular risk factors in either obese or overweight women. Materials & Methods: In the controlled pretest-posttest semi-experimental study, 18 women referred to the Alzahra sport complexes in districts 3 and 4 of Tehran were studied in 2015. The subjects were selected via random sampling method and randomly divided into two groups; physical activity and control groups. And the intervention program was conducted in the former, while the latter received no intervention. The exercise protocol consisted of 10-week (5 sessions a week) stretching exercises and aerobic activities (60 to 75% of the maximum heart beat). The serum homocystein level and lipids were measured both at the start and 48 hours after the exercises. Data was analyzed by SPSS 16 software using paired T and independent T tests. Findings: After the exercises, the mean serum homocysteine level in physical activity group significantly decreased than control group (p=0.001). Nevertheless, the difference between the lipid levels of physical activity and control groups was not significant (p>0.05). Conclusion: Reducing the serum homocysteine concentration, 10-week physical activity might also reduce the risk factors of cardiovascular diseases in either obese or overweight women.

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Background: The aim of this study was to assess the correlation between nutritional knowledge, Attitude, and Practice (KAP) and physical activity (PA) on the quality of life (QOL) in women with breast cancer (BC). Methods: This cross-sectional study involved all women with BC who referred to Imam Khomeini Hospital in Tehran during the years 2018-2019 that by using Cochran formula, 220 of them were selected by convenience sampling and answered the questionnaire including Global Physical Activity Questionnaire (GPAQ), Nutritional Knowledge, Attitude, Practice Survey (KAP) and Quality of life Questionnaire for breast cancer patients (QLQ-30). To determine the share of nutritional variables and physical activity (PA) in predicting QOL, standard multiple regression was used by SPSS 22 software. Results: The findings of the study showed that the BC patients’ PA (109.61±110.831), QOL (49.805±16.830) and KAP (K= 46.028±11.879; A=45.540±19.754; P=46.870±12.362) were not in a good condition.The best functional outcomes of QLQ-30 questionnaire were found for social functioning (73.560±26.873) and role functioning (73.560±26.873) subscales whereas emotional functioning was found lowest (58.257±24.298).Also, the results showed thatNutrition-RelatedKnowledge (β=144; P=0.036), Attitudes (β=160; P=0.038), and Practice (β=0.596; P=0.045) and PA (β=0.042; P=0.001) were significant factorsinpredictingcancer patients’ quality of life. Conclusion: The study showed that active patients have a good QOL, also, right nutritional choices and performance by the patients can result in better quality of life, therefore, the patients should receive special interventions at this time.

Aims: Certain exercises can develop the antioxidant system. Fenugreek supplementation containing antioxidant capacity and minerals may increase the benefits of exercises. The current study aimed at investigating the effect of Pilates training with fenugreek supplement on Total Antioxidant Capacity (TAC) and minerals in active women. Methods & Materials: The current study was with a quasi-experimental design was conducted on 36 active women aged 21-28 years randomly assigned into four groups: training, supplement, training plus supplement, and control. The training groups performed six weeks of Pilates training with the intensity of 60%-80% of maximal heart rate, three times a week for six weeks. Supplement groups received 500 mg fenugreek seeds daily for six weeks. Before and after the intervention, TAC and minerals (calcium, phosphorus, and iron) were measured. Data were analyzed by two-way ANOVA, Tukey post hoc test, and paired t-test at significant levels of P<0.05. Findings: In two variables, TAC and calcium, the time effect was significant, in other words, regardless of the group factor, there were significant differences between the post-test and pre-test of TAC and calcium variables in the experimental groups. The interaction of time-group was significant in TAC variable (P<0.05). The effect of the group was not significant in any of the variables. Conclusion: The obtained results suggested that one period of Pilates training and the use of fenugreek supplement alone and in combination could possibly prevent oxidative stress induced by exercise and could be effective in enhancing TAC and increasing calcium levels in active women.