Acne is a chronic in ammatory disease of the pilosebaceous glands which is an aesthetically unpleasant and embarrassing condition. Certain factors can precipitate or aggravate this condition. is study was done to identify factors believed by the patients that can precipitate or aggravate acne in our population. One hundred (100) patients with acne attending the Dermatology & Venereology outpatient Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, from April 2014 to September 2014 were enrolled for the study. Patients were enquired about factors which aggravated or precipitated their acne by using a structured questionnaire and recorded for statistical analysis. Female patients (65%) and students (50%) su ered more from acne. Younger patients were more a ected by the condition (56%). Use of topical steroid 32%, exposure to sunlight 23%, cosmetics 24%, stressful events, food 14%, skin pricking 16%, premenstrual period and dry weather 7% were found to be responsible for acne aggravation in those participants. Acne is more predominant in female patients and in younger age Patient perception on precipitating or aggravating factors for acne

Background: Tuberculosis continues to be a health problem in many countries. There may be simultaneous multiple organ involvement. Diagnosis of one organ disease may lead to missing off diagnosis of other organ involvement.Objectives: The present study was done to analyze the association of cutaneous tuberculosis with pulmonary tuberculosis.Material and methods: Through purposive sampling a total of 23 patients of suspected cutaneous tuberculosis were primarily enrolled in this cross sectional study. History was taken and examinations were done to find out types of cutaneous lesions and to explore a pulmonary involvement. Investigations including CBC with ESR, Mantoux test and Skin biopsy were done for each and every patient. Those who had cutaneous tuberculosis on histopathology chest x-ray were done to detect pulmonary lesions. After investigations 2 patients were excluded due to absence of tubercular infection. Finally 21 patients were included in this study. Data were collected in a predesigned structured questionnaire.Results: Out of 21 patients 16 (76.19%) were male and 5(23.81%) were female with a male to female ratio of 3.2:1. Age range varies from 5-70 years with a mean of 29.76±18.2 years. MT was positive in 76.20% of patients. CXR showed 23.81% of the patients with cutaneous TB had simultaneous pulmonary involvement. The association is statistically significant (p<0.05).Conclusions: Patients with Cutaneous tuberculosis may have pulmonary involvement in a statistically significant number. In any patient with cutaneous TB, meticulous systemic examinations and relevant investigations have to be done to explore pulmonary involvement. DOI: 10.3329/bmrcb.v36i2.6988Bangladesh Med Res Counc Bull 2010; 36: 57-60

Lichen planus is an inflammatory keratotic dermatosis of unknown etiology, occurs in 0.5-1.9% of the population. 1-2 Its classical clinical presentation is characterized by flat-topped, polygonal, papules or plaques of violet color. It affects primarily the flexure surface of the wrists, thighs, distal third of lower extremities, abdomen, genitals, nails and oral mucosa. Lichen planus is a pruritic, inflammatory disease of the skin, mucous membrane and hair follicles. It occurs throughout the world in all races. It is a common skin disease, comprising more than 0.5% of all dermatological visits. It may be familial in 1-2% of cases. 3

<p>The clinico-epidemiological data of 276 childhood psoriasis were studied. The mean age was 7.64 years (range 1 day to 15 years). There was no complain of any discomfort in 198 cases. Itching was present in 67 cases and burning in 11 cases. Plaque psoriasis was the most common type (68.8%) followed by guttate (18.8%). Erythrodermic and pustular psoriasis were found in 2.2% and 1.5% cases. Scalp was the most frequently affected site (75.36%) followed by extensors of extremities (41.3%), trunk (37.7%), palm and/or sole (13.0%) and diaper area (11.6%). Nail involvement was found only in 8%, joint was affected in 3.6% and only 2.2% children with psoriasis were erythrodermic. In Bangladeshi children with psoriasis, plaque is the most common type and scalp is the mostly affect site. Nail and joint involvement is less common. Pustular and erythrodermic psoriasis is rare.</p>

Hematologic malignancies can present with various cutaneous manifestations. These include specific cutaneous diseases & non-specific cutaneous lesions. Non-specific skin lesions are more common in patients with hodgkins diseases. Generalized severe pruritus may precede other findings of Hodgkins disease by many months . So an evaluation for underlying lymphoma should be considered in patient with severe itching. Leukemia cutis (specific skin lesions of Leukemia) most commonly occurs concomitant with or following the diagnosis of leukemia. The skin may also be the site of relapse of leukemia after chemotherapy. Uncommonly leukemia cutis may be identified while the bone marrow & peripheral blood are normal. Those patients are classified as aleukemic leukemia cutis. This cross sectional observational study was carried out in the Hematology department of Bangabandhu Sheikh Mujib Medical University from January 2012 to January 2013 with the intention to know the prevalence of skin manifestations of hematologic malignancies & to help diagnose and manage hematologic malignancies in some extent. Total 127 consecutive patients who were already diagnosed as haematological malignancies & hospitalized were evaluated at the period of one year. Different types of cutaneous lesions were found in our study population, Infections were the highest number, 32(25.19%) patients suffering from various infections. Other findings includemalignant infiltration, 10(7.87%); hemorrhagic 121 lesions (petechia and ecchymosis), 17(13.38%); drug reaction, 5(3.93%); gingival hyperplasia, 3(2.36%); pruritus, 23(18.11%); pigmentation, 20(15.74%); prurigo, 8(6.29%) and ichthyosiform lesion, 19(14.96%).Bangladesh Med J. 2014 Sep; 43 (3): 121-124

Background: Tazarotene is a new 3 rd generation topical acetylenic retinoid. It normalizes keratinocyte differentiation, reduces keratinocyte proliferation and decreases expression of inflammatory markers. Tazarotene was approved by US FDA in 1997 for acne vulgaris. Objectives: To evaluate the efficacy and safety of topical tazarotene 0.1% cream in the treatment of facial acne. Materials and methods: 67 patients with facial acne in the age range of 13-30 years were enrolled in the study. Purposive sampling was done. Patients were treated with topical Tazarotene cream (0.1%) and were instructed to apply the medication as a thin film over the affected area in the evening once daily for 12 weeks. Follow-up was done at 2 nd , 4 th week, 8 th week and at 12 th week. Results: Of the 67 patients, 53% got remission, 9% had good response, 34% had poor response and there was no response in 4% of the patients by 12 weeks of treatment. Among the patients, 9 (13.43%) developed mild side effects. Conclusion: Topical tazarotene cream (0.1%) is a effective and safe treatment option for acne vulgaris affecting face. It is mostly effective in grade-1 and grade-2 acne.

<p class="Abstract">This randomized controlled clinical trial was conducted to assess the efficacy and safety of intralesional triamcinolone acetonide in the treatment of chronic hand eczema comparing with topical clobetasol propionate. A total 60 patients of chronic hand eczema were recruited in the study. Thirty patients (Group A) were treated with intralesional triamcinolone acetonide and the rest 30 (Group B) with topical clobetasol propionate. Severity and improvement were assessed using Hand Eczema Severity Index (HECSI) score. The patients of both groups were followed up at 4^th week and 12^th week. In Group A, median HECSI score at baseline, 4^th week and 12^th week were 3, 20 and 20 respectively; whereas these scores were 54, 10 and 8 in Group B. In both groups, HECSI score was decreased gradually but the rate was higher in Group B than Group A (p&lt;0.05). Thinning of skin, an adverse effect, was seen in patients of both the intralesional triamcinolone acetonide (10%) and topical clobetasol propionate (16.7%) groups (p&gt;0.05). The result of this study demonstrates that intralesional triamcinolone acetonide is effective and safe in treating chronic hand eczema but less effective than the topical clobetasol.</p>

DOI: http://dx.doi.org/10.3329/jdmc.v20i2.10548 J. Dhaka Med. Coll. 2011; 20(2): 188-192