Acne is a chronic in ammatory disease of the pilosebaceous glands which is an aesthetically unpleasant and embarrassing condition. Certain factors can precipitate or aggravate this condition. is study was done to identify factors believed by the patients that can precipitate or aggravate acne in our population. One hundred (100) patients with acne attending the Dermatology & Venereology outpatient Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, from April 2014 to September 2014 were enrolled for the study. Patients were enquired about factors which aggravated or precipitated their acne by using a structured questionnaire and recorded for statistical analysis. Female patients (65%) and students (50%) su ered more from acne. Younger patients were more a ected by the condition (56%). Use of topical steroid 32%, exposure to sunlight 23%, cosmetics 24%, stressful events, food 14%, skin pricking 16%, premenstrual period and dry weather 7% were found to be responsible for acne aggravation in those participants. Acne is more predominant in female patients and in younger age Patient perception on precipitating or aggravating factors for acne

Hematologic malignancies can present with various cutaneous manifestations. These include specific cutaneous diseases & non-specific cutaneous lesions. Non-specific skin lesions are more common in patients with hodgkins diseases. Generalized severe pruritus may precede other findings of Hodgkins disease by many months . So an evaluation for underlying lymphoma should be considered in patient with severe itching. Leukemia cutis (specific skin lesions of Leukemia) most commonly occurs concomitant with or following the diagnosis of leukemia. The skin may also be the site of relapse of leukemia after chemotherapy. Uncommonly leukemia cutis may be identified while the bone marrow & peripheral blood are normal. Those patients are classified as aleukemic leukemia cutis. This cross sectional observational study was carried out in the Hematology department of Bangabandhu Sheikh Mujib Medical University from January 2012 to January 2013 with the intention to know the prevalence of skin manifestations of hematologic malignancies & to help diagnose and manage hematologic malignancies in some extent. Total 127 consecutive patients who were already diagnosed as haematological malignancies & hospitalized were evaluated at the period of one year. Different types of cutaneous lesions were found in our study population, Infections were the highest number, 32(25.19%) patients suffering from various infections. Other findings includemalignant infiltration, 10(7.87%); hemorrhagic 121 lesions (petechia and ecchymosis), 17(13.38%); drug reaction, 5(3.93%); gingival hyperplasia, 3(2.36%); pruritus, 23(18.11%); pigmentation, 20(15.74%); prurigo, 8(6.29%) and ichthyosiform lesion, 19(14.96%).Bangladesh Med J. 2014 Sep; 43 (3): 121-124

Tinea (pityriasis) versicolor is a superficial fungal infection and one of the most commonly found pigmentary disorders of the skin caused by the yeast Malassezia. Multiple topical as well as systemic therapies are available for treatment. Systemic therapies are used for extensive disease, frequent relapse or where topical agents have failed. The aim that translates the rationale of the study was to compare the efficacy, safety, tolerability and cost effectiveness of oral ketoconazole dose 200mg daily for 7 days versus a single dose of 400 mg of itraconazole in the treatment of tinea versicolor. A total of 64 patients (aged 18-50 years) were selected for the study from the period of June 2019 to November 2019 in the Department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University, Bangladesh. Cases having extensive involvement were diagnosed clinically and confirmed by wood's lamp and KOH microscopy was taken. Patients were randomly allocated into equal groups. Group A was given oral ketoconazole dose 200mg daily for 7 days and Group B has given a single dose of 400 mg of itraconazole. 47 (73.4%) male and 17(26.6%) female were included in the study. The mean age of group A was 29.2(SD±8.6) and in group B 28.2(SD±8.5) years. The mean duration of the disease in group A was 3.9(±2.7) months and 3.5(±2.2) months in group B. In group A clinical responders was found cure 25(78.1%), improvement 5(15.6%) and failure in 2(6.2%) and in group B it was found cure 22(68.8%), improvement 7(21.87%) and failure 3(9.4%) at one month. At two months in the group A clinical responder was found to cure 22(68.8%), improvement 5(15.6%), failure in 3(9.4%) and relapse 2(6.2%). In group B it was found cure 18(56.2%), improvement 6(18.75%), failure 4(12.5%) and relapse 4(12.5%). Both oral ketoconazole dose 200mg daily for 7 days versus single dose 400 mg of itraconazole can be effective in the treatment of tinea versicolor with extensive involvement. CBMJ 2020 July: Vol. 09 No. 02 P: 26-33

Leukemia and Lymphoma can present with various cutaneous manifestations. These include specific cutaneous diseases and non-specific cutaneous lesions. Non-specific skin lesions are more common in patients with Hodgkins diseases. Leukemia cutis (specific skin lesions of Leukemia) most commonly occurs concommitent with or following the diagnosis of leukemia. The skin may also be the site of relapse of Leukemia after chemotherapy. Uncommonly leukemia cutis may be identified while the bone marrow and peripheral blood are normal. Those patients are classified as aleukemic leukemia cutis. The objective of this study is to know the prevalence of skin manifestations of hematologic malignancies and to help the diagnosis and management of hematologic malignancies in some extent. It is a cross sectional observational study in which the skin lesions of the patients in hematologic malignancies who were already diagnosed & hospitalized in the hematology department of Bangabandhu Sheikh Mujib Medical University were evaluated in the period of one year. We found malignant infiltrative lesions & hemorrhagic findings both were predominate in leukemia. Infections were predominant in both Leukemia & Lymphoma. CBMJ 2015 July: Vol. 04 No. 02 P: 31-34

Introduction: This case report highlighting the presence of keratoacanthoma and verruca vulgaris over the lesion of porokeratosis of mibelli. Case Report: In this case a 50-year-old housewife came with large well-defined asymptomatic plaque over the upper part of back of the trunk for last 10 years. After evaluation we got the presence of keratoacanthoma and verruca vulgaris on the plaque of porokeratosis of mibelli. Discussion: Porokeratosis is a clonal expansion of keratinocytes. Among the neoplasm squmous cell carcinoma (SCC) is the most commonly reported malignancy in porokeratosis. But in our case we didn’t find lesion of SCC. Porokeratosis of Mibelli, Keratoacanthoma and Verruca vulgaris have an association with human papilloma virus(HPV). This eithopathogenesis may be related to our clinical finding. Conclusion: There were reporting of squmous cell carcinoma or keratoacanthoma on Porokeratosis of Mibelli. But in our case we found both Keratoacanthoma and Verruca Vulgaris over Porokeratosis of Mibelli. Medicine Today 2021 Vol.33(2): 172-175

No abstract

Herpes zoster (commonly referred to as "shingles") results .from reactivation of the varicella-zoster virus infection, or chickenpox. Were as varicella is generally a disease of childhood, herpes zoster becomes more common with increasing age Factors that decrease immune function, such as human immunodeficiency virus infection, chemotherapv, malignancies and chronic corticosteroid use, may also increase the risk of developing herpes zoster. Reactivation of latent varicella-zoster virus from dorsal root ganglia is responsible.for lhe classic dermatomal rash and pain that occur with herpes zoster. Burning pain typically precedes the rash by several days and can persist for several months after the rash resolves. With post herpetic neuralgia, a complication of herpes zoster, pain may persist well after resolution of the rash and can be highly debilitating. Although the diagnosis of the conditions is generally straightforward, treatment can be frustrating for the patient and physician. Approaches to management include treatment of the herpes zoster infection and associated pain, prevention of post herpetic neuralgia, and control of the neuropathic pain until the condition resolves. Herpes zoster is contagious to those who have not had varicella or have not received the varicella vaccine. The role of the varicella vaccine in preventing herpes zoster is uncertain, but is being studied. The management of herpes zoster is challenging because many patients develop troublesome complication. So, appropriate management o/'herpes zoster is very important to avoid complication. On the other hand prevention is better than cure. Immunization with varicella zoster virus vaccine may boost humoral and cell mediated and decrease the incidence of zoster in population. So effectiveness of a vaccination program need to be evaluated. immunity DOI: http://dx.doi.org/10.3329/bmj.v41i3.18961 Bangladesh Medical Journal 2012 Vol.41(3): 53-56