“…The clinical manifestation of acne is generally polymorphic eruptions ranging from the formation of open and closed comedones to erythematous pustules and papules, while, in more severe cases, it may include deep pustules, inflammatory nodules, and pseudocysts (Kucharska, Szmurło, & Sinska, 2016;Snigdha et al, 2016). Acne distribution usually correlates with the topmost density of the body's pilosebaceous units (Snigdha et al, 2016;Walsh, Efthimiou, & Dréno, 2016).…”