Acne is a chronic in ammatory disease of the pilosebaceous glands which is an aesthetically unpleasant and embarrassing condition. Certain factors can precipitate or aggravate this condition. is study was done to identify factors believed by the patients that can precipitate or aggravate acne in our population. One hundred (100) patients with acne attending the Dermatology & Venereology outpatient Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, from April 2014 to September 2014 were enrolled for the study. Patients were enquired about factors which aggravated or precipitated their acne by using a structured questionnaire and recorded for statistical analysis. Female patients (65%) and students (50%) su ered more from acne. Younger patients were more a ected by the condition (56%). Use of topical steroid 32%, exposure to sunlight 23%, cosmetics 24%, stressful events, food 14%, skin pricking 16%, premenstrual period and dry weather 7% were found to be responsible for acne aggravation in those participants. Acne is more predominant in female patients and in younger age Patient perception on precipitating or aggravating factors for acne

Ankylosing Spondylitis (AS) is a chronic inflammatory rheumatic disease principally affecting the axial skeleton. The disease can have a profound impact on life quality in terms of physical, social and psychological well-being. It has a great detrimental effect on our social and economic stability as the disease is more severe in men than in women. Work disability in AS patients is higher than expected in the general population for both male and female. Patients with AS may incur significant medical costs which accelerate steeply with increasing loss of function (BASFI) and disease activity (BASDAI). Patients with more severe disease activity are at greater risk for developing functional disability. AS influences the subjective health of the affected person, especially the physical health related QoL. BASFI, BASDAI, BASG and pain are significantly associated with SF-36 physical and mental domains in patients with AS. Pain, fatigue and stiffness are the most commonly reported symptoms of these patients. Sleep disturbance, anxiety, depression and sexual dysfunction are other factors that significantly affect patients’ quality of life.Birdem Med J 2014; 4(2): 88-93

<p class="Abstract">This randomized controlled clinical trial was conducted to assess the efficacy and safety of intralesional triamcinolone acetonide in the treatment of chronic hand eczema comparing with topical clobetasol propionate. A total 60 patients of chronic hand eczema were recruited in the study. Thirty patients (Group A) were treated with intralesional triamcinolone acetonide and the rest 30 (Group B) with topical clobetasol propionate. Severity and improvement were assessed using Hand Eczema Severity Index (HECSI) score. The patients of both groups were followed up at 4^th week and 12^th week. In Group A, median HECSI score at baseline, 4^th week and 12^th week were 3, 20 and 20 respectively; whereas these scores were 54, 10 and 8 in Group B. In both groups, HECSI score was decreased gradually but the rate was higher in Group B than Group A (p&lt;0.05). Thinning of skin, an adverse effect, was seen in patients of both the intralesional triamcinolone acetonide (10%) and topical clobetasol propionate (16.7%) groups (p&gt;0.05). The result of this study demonstrates that intralesional triamcinolone acetonide is effective and safe in treating chronic hand eczema but less effective than the topical clobetasol.</p>