Carbon dots (CDs) are relatively new and one of the most propitious nanomaterials ever known to humanity, primarily consisting of a carbonized carbon core with heteroatoms in organic functional groups attached. CDs show various fascinating properties, such as tunable excitation/emission, chemical inertness, photostability, low toxicity, good biocompatibility, ease of handling, and eco-friendliness. Due to the anomalous optical and chemical properties of the CDs, they have a wide range of applications in the fields of bioimaging, biosensing, photocatalysis, optoelectronics, etc. In this Review, we intend to cover the many strides in CDs chemistry, which is an emerging paradigm, in conjunction with the most recent discoveries of CDs with near-infrared fluorescence, phosphorescence, electroluminescence, chirality, and antibacterial activity. Our main emphasis will be on the contemporary evolution in synthetic strategies, optical properties, and biomedical applications of CDs in nanomedicine and nanotheranostics.

Compared with graphene quantum dots (GQDs), fluorine-containing GQDs (F-GQDs) present higher 1O2 generation under light irradiation and thus cause obvious toxicity to HepG2 cells. F-GQDs can be used as a photosensitizer for photodynamic therapy.

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A single-atom metal doped on carbonaceous nanomaterials has attracted increasing attention due to its potential applications as high-performance catalysts. However, few studies focus on the applications of such nanomaterials as nanotheranostics for simultaneous bioimaging and cancer therapy. Herein, it is pioneeringly demonstrated that the single-atom Gd anchored onto graphene quantum dots (SAGd-GQDs), with dendrite-like morphology, was successfully prepared. More importantly, the as-fabricated SAGd-GQDs exhibits a robustly enhanced longitudinal relaxivity (r 1 = 86.08 mM −1 s −1 ) at a low Gd 3+ concentration of 2 μmol kg −1 , which is 25 times higher than the commercial Gd-DTPA (r 1 = 3.44 mM −1 s −1 ). In vitro and in vivo studies suggest that the obtained SAGd-GQDs is a highly potent and contrast agent to obtain high-definition MRI, thereby opening up more opportunities for future precise clinical theranostics.

This community service program is carried out in Mulyajaya Village, Lasalimu Selatan District, Buton Regency. Some of the main problems that become a problem in Mulyajaya Village, Lasalimu Selatan District, Buton Regency, are the not yet optimal knowledge of the community regarding Environmental Sanitation and the lack of optimal socialization to the public about how to create and improve a healthy environment. The results of this PKM activity can be described through the role of social capital as a form of local knowledge, it can be used as a means of socializing the importance of environmental awareness. The process of increasing community knowledge about environmental improvement is carried out through three discussions namely socialization, mentoring and planning for making garbage cans and making latrines.

Cross-linking sulfonated carbon dots with Sn4+ can greatly enhance the fluorescence and lead to a higher singlet oxygen quantum yield.

The Corona Virus (Covid-19) is causing panic everywhere. Hundreds of thousands people were infected and thousands more died. The Indonesian government itself has given appeals to the community in overcoming this epidemic, so that it runs effectively and efficiently. However, in reality there are still many Indonesian people who do not heed this appeal. Therefore, this community service activity aims to assist the government in increasing public knowledge about preventing Covid-19. The method used in community service is carried out through counseling and mentoring. This activity is able to increase public knowledge and understanding about the dangers of Covid-19 and efforts to protect themselves from the implementation of 3M.

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