Zirconium-based metal-organic frameworks (Zr-MOFs) have been synthesized onto diverse substrates however thermal and acidic conditions of synthesis processing impair or carbonize the polysaccharide based substrate. Also, MOF-coated polysaccharides usually show poor mechanical properties and instability in aqueous conditions unsuitable for biomedical applications. There is no report on the synthesis of MOFs on cellulosic substrate to preserve intactness. Here, an optimized Zr-MOFs synthesis method on cotton fabric is introduced to prepare a biomedically applicable Zr-MOFs modified cellulosic fabric. The resultant fabric demonstrates an absolute wash durability with enhanced hydrophilicity and better mechanical properties with higher Zr-MOFs content. The treated fabric shows 787% and 2105% improvement in absorption capacity for Salvia officinalis (SO) and Calendula officinalis (CO) extracts and the release kinetic model of diffusion mechanism. Cotton-MOF-SO and Cotton-MOF-CO confirm antibacterial activity of 99.2% and 37.4% against Escherichia coli and 19.9% and 35.3% against Staphylococcus aureus. Finally, the cotton-MOF-CO can be considered as a biocompatible material however cotton-MOF-SO exhibits high toxicity signifying its potentiality for inducing death to cancer cells.
Improvement of curative herbal extracts effectiveness through novel drug delivery systems is a field of study for the researches nowadays. Zirconium-based metal-organic frameworks (Zr-MOFs) are one of the most capable porous nanocarriers that need a biocompatible template to be used in biomedical applications. In this work, Zr-MOF was synthesized into the wool fabric through in-situ one-pot method with different molar ratios. The final fabrics were characterized thoroughly using various techniques and the effect of components on monodispersity and nucleation tendency of Zr-MOF onto the surface of wool were explained. The resultant fabric stablished absolute wash durability, increased air-permeability up to twice and reasonable hydrophilicity. Tensile strength and young modulus decreased 30 and 1244 % and strain increased 66 %.
Salvia Officinalis
(SO) and
Calendula Officinalis
(CO) extracts were loaded onto the modified fabrics with 1154 and 1842 % increased absorption capacity. The release profiles showed domination of diffusion mechanism. The wool-MOF-SO and CO displayed both 100 % antibacterial activity against
Escherichia coli
and 60.95 and 64.64 % against
Staphylococcus aureus
because of diverse antibacterial components.
Calendula Officinalis
proved biocompatibility with human skin however
Salvia Officinalis
exhibited high toxicity.
Microbial susceptibility of the denim fabric sized by starch raises some skin health concerns about this extensively used fabric. In this work, biocompatible antibacterial denim fabric is prepared by optimized green synthesis of the copper(I) oxide (Cu 2 O) nanoparticles on the cotton fibers. The copper oxide nanoparticles were synthesized without using any toxic chemical to reduce the copper salt. As an alternative, the waste of the sugar refinery factory, molasses, was used as eco-friendly and cost-efficient material. The antibacterial activity of the samples against Candida albicans as model fungus, Escherichia coli as Gram-negative, and Staphylococcus aureus as Gram-positive model bacteria is investigated besides cytotoxicity; also, the synthesis process is optimized regarding the most biocompatible and antibacterial nanocomposite. The characterizations prove the effectiveness of the molasses for reduction of the copper salt and formation of the copper(I) oxide (Cu 2 O) nanoparticles. Synthesis of the copper(I) oxide (Cu 2 O) nanoparticles has a positive effect on the mechanical properties of the nanocomposite. The results of this work introduce a green method for sustainable development of the fabric industry; it also presents a potential application for molasses and reutilizing it.
Concerning the increasing demand for antibacterial nature-based textiles, this work deals with the modification of cotton fabric with corn silk as a natural polymer together with the in situ synthesis of copper (II) oxide nanoparticles.Copper acetate is used as a precursor of copper (II) oxide and ascorbic acid as an environmentally friendly reducing agent. The copper (II) oxide/corn silk nanocomposite cotton fabrics are evaluated by FESEM, XRD, FTIR, water absorption, and antibacterial analysis. The treated fabrics exhibit higher water absorption and FESEM images along with EDX spectra confirm the formation of copper (II) oxide nanoparticles and corn silk layer on the fabric surface. FTIR analysis also establishes effective assembling of CuO/corn silk on the cotton surface. Moreover, the antimicrobial efficiency of the nanocomposite is verified to be higher than 90% against Gram-negative and Gram-positive model bacteria comprising Escherichia coli and Staphylococcus aureus, and antifungal properties against Candida albican. Consequently, the fabrication of copper (II) oxide/corn silk nanocomposites on the cotton fabric could be potentially applied for the preparation of antibacterial medical textiles.
Hydrogels demonstrate interesting features and applications in various fields including biomedical, environmental, and smart materials. Unfortunately, they provide a favorable environment for growth of microorganisms without exhibiting adequate mechanical properties. To overcome these shortcomings and prepare a multifunctional nanocomposite, in this research a facile industrially applicable method is introduced for preparation of starch‐copper ferrite hydrogel on cotton fabric at room temperature. The preparation conditions are optimized using central composite design based response surface methodology. The magnetic properties and swelling behavior of all samples are investigated and the optimal sample is selected for further characterization. XRD pattern indicates the presence and successful synthesis of copper ferrite and magnetite in hydrogel. FE‐SEM images demonstrate unique structure shaped with nanosegments with symmetric multilateral shape and average size of 300 nm. The absorption capacity of nanocomposite rises to 3.96 g g−1 indicating 253.57% improvement, and also exhibits 100% antibacterial activity against both Gram positive and negative model bacteria. In this manner, a promising nanocomposite with verified multifunctionality is proposed even as synthesis of copper ferrite and hydrogel attachment to the fabric are also merged to single‐step via a simple method with hope of being applicable for scalable production.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.