Single-step Synthesis and Characterization of Zr-MOF onto Wool Fabric: Preparation of Antibacterial Wound Dressing with High Absorption Capacity

Abstract

Improvement of curative herbal extracts effectiveness through novel drug delivery systems is a field of study for the researches nowadays. Zirconium-based metal-organic frameworks (Zr-MOFs) are one of the most capable porous nanocarriers that need a biocompatible template to be used in biomedical applications. In this work, Zr-MOF was synthesized into the wool fabric through in-situ one-pot method with different molar ratios. The final fabrics were characterized thoroughly using various techniques and the effect of components on monodispersity and nucleation tendency of Zr-MOF onto the surface of wool were explained. The resultant fabric stablished absolute wash durability, increased air-permeability up to twice and reasonable hydrophilicity. Tensile strength and young modulus decreased 30 and 1244 % and strain increased 66 %. Salvia Officinalis (SO) and Calendula Officinalis (CO) extracts were loaded onto the modified fabrics with 1154 and 1842 % increased absorption capacity. The release profiles showed domination of diffusion mechanism. The wool-MOF-SO and CO displayed both 100 % antibacterial activity against Escherichia coli and 60.95 and 64.64 % against Staphylococcus aureus because of diverse antibacterial components. Calendula Officinalis proved biocompatibility with human skin however Salvia Officinalis exhibited high toxicity.

Spectroscopic Characterization, Cyclic Voltammetry, Biological Investigations, MOE, and Gaussian Calculations of VO(II), Cu(II), and Cd(II) Heteroleptic Complexes

“…DFT coupled with the [LANL2DZ/6-31G+(d,p)] mixed basis set − was employed to optimize geometrically the molecular structure of all isolated compounds within atom numbering as represented in Figure . The results displayed in Table 8Sa,b showed that (i) the bond lengths of the most characteristic functional groups for isolated complexes correlate with the IR band expansions, confirming their participation in the coordination process, and (ii) the bond angles of the [Cu­( o -BMP)­(H 2 O) 2 ]·2H 2 O and [Cd­( o -BMP)­(H 2 O) 2 ]·2H 2 O complexes correlate a distorted octahedral arrangement, while the [VO­( o -H 2 BMP)­(SO 4 )]·4H 2 O exists as a square-pyramidal geometry supporting the configurations concluded by UV–visible spectral analyses …”

Investigation of the Shrinkage and Air Permeability of Woolen Blankets and Blankets Made with Regenerated Wool

“…As a result, entanglement should be more difficult for the adjacent woolen fibers or yarns; this may be one of the reasons for the better permeability, and therefore the fabrics with regenerated wool had higher air permeability than the woolen fabrics. With the use of blends with other fibers [ 25 , 26 , 28 , 29 ] and surface treatment [ 30 , 31 , 33 , 34 ], the air permeability can be controlled. It was established that combined twill had the highest air permeability and derived basket weave the lowest.…”

“…This property is highly related to the porosity of the fabric, of which the methods of establishment are described in reference [ 23 ]. The structural parameters, such as the raw material, linear density of the warp and weft yarns, number of yarn twists, warp and weft density, warp and weft crimp, and weave, influence the porosity and air permeability of fabrics [ 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ]. The influence of the structure of woolen fabric on its comfort properties and shrinkage has been described in only a few works [ 25 , 26 ]; thus, such investigations are very important.…”

Biocompatible Antibacterial Denim Fabric Prepared via Green Synthesis of the Copper Oxide Nanoparticles Using Raw Sugar Molasses

“…[4] One of the methods for preparing antibacterial fabrics is the synthesis of metal-based nanoparticles on them. [5][6][7] Among the metal oxides, copper-based nanoparticles have high antibacterial activities. [8][9][10][11][12] Facile preparation process and high surface area introduced by their nano-size, make them favorable antibacterial agents.…”