Preparation of long-lasting antibacterial wound dressing through diffusion of cationic-liposome-encapsulated polyhexamethylene biguanide

Ahani, Elnaz; Montazer, Majid; Mianehro, Ali; Samadi, Nasrin; Toliyat, Tayebeh; Rad, Mahnaz Mahmoudi

doi:10.1016/j.reactfunctpolym.2021.105092

Cited by 22 publications

(9 citation statements)

References 41 publications

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“…13 On the other hand, PHMB is a colorless, odorless solution with a broad antimicrobial spectrum, lowtoxicity profile, and high tissue compatibility. 30 Therefore, PHMB can be considered when using antiseptic instead of NS in peristomal area care.…”

Section: Discussionmentioning

confidence: 99%

Comparison of normal saline and antiseptic solution effect on the early peristomal infection rates of patients with percutaneous endoscopic gastrostomy tubes: A randomized double‐blind study

et al. 2023

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BackgroundThis study's aim was to compare the efficacy of normal saline (NS) with that of antiseptic solution in early peristomal skin care after percutaneous endoscopic gastrostomy placement in terms of peristomal infection incidence.MethodsThis was a randomized controlled double‐blind study conducted at a university hospital between December 2019 and April 2021. All patients who underwent percutaneous endoscopic gastrostomy and met the inclusion and exclusion criteria were included in the study. The study population consisted of 64 patients randomized to group 1: NS (n = 31) and group 2: 0.1% polyhexamethylene biguanide and 0.1% betaine (PHMB‐B; n = 33). Daily peristomal skin care was performed for 7 days, starting 24 h after insertion. Peristomal skin was evaluated by two blinded investigators before each dressing, and findings were recorded. Data analysis was performed with descriptive statistics; chi‐square analysis; and exact, Shapiro‐Wilk, Mann‐Whitney U, and Cochran Q tests.ResultsThere was no statistically significant difference between the groups in terms of peristomal infection rates (group 1: 12.9%, group 2: 9.07%; P > 0.05). Redness increased from day 4 in group 1 and day 5 in group 2, and exudate increased from day 5 in both groups. There is a statistical difference in the number of patients between the days when redness and exudate appear and increase.ConclusionBoth NS and PHMB‐B solutions can be preferred in peristomal care. However, NS may be the first choice for early peristomal care that does not show signs of infection, because it is not irritating and allergic and is cost‐effective.

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Section: Discussionmentioning

confidence: 99%

Comparison of normal saline and antiseptic solution effect on the early peristomal infection rates of patients with percutaneous endoscopic gastrostomy tubes: A randomized double‐blind study

et al. 2023

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“…The absorption intensity at 570 nm was recorded and cell viability was calculated based on the ratio of sample absorption to control absorption. [ 44 ]…”

Section: Methodsmentioning

confidence: 99%

Biocompatible Antibacterial Denim Fabric Prepared via Green Synthesis of the Copper Oxide Nanoparticles Using Raw Sugar Molasses

et al. 2022

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Microbial susceptibility of the denim fabric sized by starch raises some skin health concerns about this extensively used fabric. In this work, biocompatible antibacterial denim fabric is prepared by optimized green synthesis of the copper(I) oxide (Cu 2 O) nanoparticles on the cotton fibers. The copper oxide nanoparticles were synthesized without using any toxic chemical to reduce the copper salt. As an alternative, the waste of the sugar refinery factory, molasses, was used as eco-friendly and cost-efficient material. The antibacterial activity of the samples against Candida albicans as model fungus, Escherichia coli as Gram-negative, and Staphylococcus aureus as Gram-positive model bacteria is investigated besides cytotoxicity; also, the synthesis process is optimized regarding the most biocompatible and antibacterial nanocomposite. The characterizations prove the effectiveness of the molasses for reduction of the copper salt and formation of the copper(I) oxide (Cu 2 O) nanoparticles. Synthesis of the copper(I) oxide (Cu 2 O) nanoparticles has a positive effect on the mechanical properties of the nanocomposite. The results of this work introduce a green method for sustainable development of the fabric industry; it also presents a potential application for molasses and reutilizing it.

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“…C. albicans , ATCC 10231 was used and the same method was used only the culture was different (sabouraud dextrose broth and sabouraud dextrose agar) with the incubation temperature of 30 °C. [ 48 ]…”

Section: Methodsmentioning

confidence: 99%

Preparation of Antibacterial Cellulose Fabric via Copper (II) Oxide and Corn Silk (Stigma maydis) Nanocomposite

et al. 2022

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Concerning the increasing demand for antibacterial nature-based textiles, this work deals with the modification of cotton fabric with corn silk as a natural polymer together with the in situ synthesis of copper (II) oxide nanoparticles.Copper acetate is used as a precursor of copper (II) oxide and ascorbic acid as an environmentally friendly reducing agent. The copper (II) oxide/corn silk nanocomposite cotton fabrics are evaluated by FESEM, XRD, FTIR, water absorption, and antibacterial analysis. The treated fabrics exhibit higher water absorption and FESEM images along with EDX spectra confirm the formation of copper (II) oxide nanoparticles and corn silk layer on the fabric surface. FTIR analysis also establishes effective assembling of CuO/corn silk on the cotton surface. Moreover, the antimicrobial efficiency of the nanocomposite is verified to be higher than 90% against Gram-negative and Gram-positive model bacteria comprising Escherichia coli and Staphylococcus aureus, and antifungal properties against Candida albican. Consequently, the fabrication of copper (II) oxide/corn silk nanocomposites on the cotton fabric could be potentially applied for the preparation of antibacterial medical textiles.

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Preparation of long-lasting antibacterial wound dressing through diffusion of cationic-liposome-encapsulated polyhexamethylene biguanide

Cited by 22 publications

References 41 publications

Comparison of normal saline and antiseptic solution effect on the early peristomal infection rates of patients with percutaneous endoscopic gastrostomy tubes: A randomized double‐blind study

Comparison of normal saline and antiseptic solution effect on the early peristomal infection rates of patients with percutaneous endoscopic gastrostomy tubes: A randomized double‐blind study

Biocompatible Antibacterial Denim Fabric Prepared via Green Synthesis of the Copper Oxide Nanoparticles Using Raw Sugar Molasses

Preparation of Antibacterial Cellulose Fabric via Copper (II) Oxide and Corn Silk (Stigma maydis) Nanocomposite

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