Research objective. To stratify the main purulent-inflammatory diseases of maxilla-facial region (PID MFR) by frequencies and limits. To assess mortality in PID MFR. To determine the number of patients with PID MFR and concomitant diabetes mellitus.Resources and Methods. Medical documentation on 9550 patients with PID MFR hospitalized at F.I. Inozemtsev Municipal Clinical Hospital have been analyzed.Research results. The prevalence of purulent-inflammatory diseases remains at a fairly high level. PID MFR occur more often in people of young, able-bodied, age, 18–44 years. The introduction of quarantine measures due to the new coronavirus infection COVID-19 led to an increase in severe forms of PID MFR. There is a decrease in lethality from PID MFR.
ятность наступления летального исхода с учетом влияния других факторов подтвердили, что олокизумаб значимо повышает шансы на выздоровление пациентов: ОШ 2,41 (95% ДИ 1,64-3,54, р<0,001). Кроме того, олокизумаб способствовал более быстрому и выраженному снижению уровня С-реактивного белка. Уже на 2-й день терапии в группе олокизумаба уровень СРБ был почти в 2 раза ниже, чем в группе сравнения (медиана показателя составила 13 [5,6; 28,55] и 25 [15,3; 79,25] мг/л в группах олокизумаба и сравнения соответственно).Заключение. Полученные результаты исследования подтверждают клинические данные об эффективности олокизумаба в качестве патогенетической терапии COVID-19.
Material and methods. The authors presented the experience of treating 15 patients with a cerebral form of mucormycosis of the maxillofacial region, which arose against the background of a new coronavirus infection associated with SARS-CoV-2.
Results and conclusion. The importance of timely initiation of radical surgical treatment of this pathology for the prevention of the spread of foci of destruction in the bone tissue is shown.
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