Research objective. To stratify the main purulent-inflammatory diseases of maxilla-facial region (PID MFR) by frequencies and limits. To assess mortality in PID MFR. To determine the number of patients with PID MFR and concomitant diabetes mellitus.Resources and Methods. Medical documentation on 9550 patients with PID MFR hospitalized at F.I. Inozemtsev Municipal Clinical Hospital have been analyzed.Research results. The prevalence of purulent-inflammatory diseases remains at a fairly high level. PID MFR occur more often in people of young, able-bodied, age, 18–44 years. The introduction of quarantine measures due to the new coronavirus infection COVID-19 led to an increase in severe forms of PID MFR. There is a decrease in lethality from PID MFR.
The paper describes two clinical cases of treatment of patients with noma. This disease is extremely rare in the Russian Federation, and therefore its diagnosis causes difficulties, and incorrect routing of patients, due to diagnostic mistakes, leads to an increase in the time before the start of specialized care. Rapid progression of wet gangrene, in the absence of timely diagnosis and qualified treatment, leads to extensive defects of the maxillofacial region, severe intoxication, sepsis. In the first case, after surgical treatment of noma, the patient developed an extensive tissue defect of the left half of the face, which in the future will require reconstructive surgical treatment. In the second case, after surgical treatment, the patient had an extensive tissue defect in the middle zone of the face, and systemic disorders against the background of intoxication led to the death of the patient on the 7th day after hospitalization. Both clinical cases confirm the role of immunosuppression in the etiology of noma.
Material and methods. The authors presented the experience of treating 15 patients with a cerebral form of mucormycosis of the maxillofacial region, which arose against the background of a new coronavirus infection associated with SARS-CoV-2.
Results and conclusion. The importance of timely initiation of radical surgical treatment of this pathology for the prevention of the spread of foci of destruction in the bone tissue is shown.
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