The sensitivity and specificity of Brucella agglutination tests

Mert, Ali; Özaras, Reşat; Tabak, Fehmı; Bilir, Muammer; Yılmaz, Mesut; Kurt, Celali; Öngören, Şeniz; Tanriverdi, Melike; Öztürk, Recep

doi:10.1016/s0732-8893(03)00081-6

Cited by 83 publications

(64 citation statements)

References 8 publications

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“…Similar results were obtained by [28,29], who reported 95.7% and 96% agreement respectively between the RBPT and SAT tests. Other investigators reported 100% agreement with [30] RBPT SAT (≥1:160) 2ME …”

Section: Discussionmentioning

confidence: 94%

Prevalence of Brucellosis among High Risk Groups in Northern State, Sudan

Zein¹,

Sabahelkhier²

2015

nova-jmbs

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Aim this study was to determine the prevalence of brucellosis in various occupations in Northern State, Sudan, during 2012. A total of 753 serum samples (from 21 veterinarian, 39 meat inspectors, 407 abattoir workers and 286 animal handlers) in different localities were collected and screened for brucella antibodies by using Rose Bengal Plate Test (RBPT), Serum Agglutination Test (SAT) and 2 Mercaptoethanol Test(2MET). Then information's of occupation, age, sex, kind of work were recorded. Seroprevalence of brucellosis in veterinarians, meat inspectors, abattoir workers and animal handlers was 9.5%, 15.3%, 24.4% and 26.5% respectively. The variations in antibodies detected by RBPT, SAT and 2 ME test in the high risk individuals. Study documents the serological evidence of Br. abort infection in high risk groups in Northern State particularly in Sudan, where RBPT can be used successfully in hospitals as screening test.

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Section: Discussionmentioning

confidence: 94%

Prevalence of Brucellosis among High Risk Groups in Northern State, Sudan

Zein¹,

Sabahelkhier²

2015

nova-jmbs

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“…The diagnosis of brucellosis is usually based on clinical evaluation and laboratory results. Generally, the diagnosis of brucellosis needs to be confirmed by a serum agglutination test or isolation of the organism from blood or other sterile samples [14,15]. Though blood culture is the gold standard in the diagnosis of bacteremia, more than three days are required for the final results to be available, and the sensitivity is low.…”

Section: Discussionmentioning

confidence: 99%

Clinical features and serum profile of inflammatory biomarkers in patients with brucellosis

Liu

Zhao

2017

J Infect Dev Ctries

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Introduction: Brucellosis is a zoonosis caused by Brucella, a highly infectious Gram-negative coccobacillus that has been isolated from a variety of mammals. Brucella melitensis is considered the most common cause of human brucellosis. The aim of this retrospective study was to evaluate the diagnostic value of serum parameters that relate to Brucella melitensis infection. Methodology: This investigation retrospectively analyzed the clinical laboratory tests and symptoms of brucellosis, which was confirmed by microbiological and serological methods. A total of 36 patients (31 males, 5 females; mean age 49.17 ± 13.56 years) admitted with brucellosis were included in the study over a three-year period between 2012 and 2015 in Peking University People's Hospital (PKUPH). Results: A statistically significant increase was observed in C-reactive protein and erythrocyte sedimentation rate in patients with low titers of serum antibody when compared with those with high titers. No difference was observed between the two groups with respect to the other serum parameters such as procalcitonin or white blood cell count. Two blood culture systems also yielded different results. Conclusions: In this study, we demonstrated that culture can be improved by using multiple blood culture systems to isolate Brucella melitensis. We also found the different role of inflammatory markers play during the process of brucellosis. The present study may be a helpful reference in the diagnosis of brucellosis.

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“…İndirekt ELISA, brusellozis taramasında tek başına veya RBPT'e ek olarak kullanılabilecek iyi bir test olabilir [18][19][20][21] . Serolojik testlerin karşılaştırıldığı diğer çalış-malarda ELISA'nın duyarlılık ve özgüllüğü STAT 'a eşit veya daha yüksek bulunmuştur 5,8,19,21,22 .…”

Section: Tartıșmaunclassified

Combination of The Serological Tests For The Diagnosis of Brucellosis in Endemic Areas

Balcı¹,

Kader²,

Yılmaz³

et al. 2014

Kafkas J Med Sci

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AIM: The aim of the study is to analyze the effi ciency of combination of RBPT, STAT and ELISA tests on patients with brucellosis where the diagnosis is dependent on the compatible clinical and epidemiological fi ndings with negative RBPT and/or STAT test results. METHODS: GirișBruselloz, tüm dünyada görülebilen zoonotik bir hastalık olup ülkemizde endemiktir. Halen önemli bir halk sağlığı problemi olan bruselloz, herhangi bir organı tutabilen sistemik bir enfeksiyon hastalığıdır. Multisistemik bir hastalık olması ve birçok hastalıkla kolayca karışabilen değişik belirti ve klinik bulgularla seyretmesi nedeniyle enfeksiyonun kesin tanısı, sadece klinik belirti ve bulgulara dayanılarak konulamaz.Bruselloz tanısı hastanın öyküsü, klinik belirti ve bulguları, rutin hematolojik ve biyokimyasal laboratuar testleri, radyolojik tetkikleri ve brusellaya özgü mikrobiyolojik tanı metotları birlikte değerlendirilerek yapılmalıdır. Brusellozun laboratuar tanısı, bakterinin klinik örneklerden izolasyonu, kan serumunda brusella antikor yanıtlarının gösterilmesi veya moleküler yöntemlerle mikroorganizmaya özgü nükleik asit tayininin yapılmasından ibarettir.

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The sensitivity and specificity of Brucella agglutination tests

Cited by 83 publications

References 8 publications

Prevalence of Brucellosis among High Risk Groups in Northern State, Sudan

Prevalence of Brucellosis among High Risk Groups in Northern State, Sudan

Clinical features and serum profile of inflammatory biomarkers in patients with brucellosis

Combination of The Serological Tests For The Diagnosis of Brucellosis in Endemic Areas

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