2010
DOI: 10.1586/edm.10.9
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Surgical management of vitiligo

Abstract: Vitiligo is a common condition characterized by hypopigmented and/or depigmented spots on the skin, affecting approximately 1-2% of the world population. Until approximately 30 years ago, it was exclusively treated by medical therapies. The most commonly used medical therapies include topical steroids, calcineurin inhibitors and phototherapy. Lesions on the face and neck respond the best to medical therapies, followed by lesions on the proximal extremities and trunk, while those distributed over acral parts of… Show more

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Cited by 5 publications
(8 citation statements)
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References 67 publications
(77 reference statements)
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“…95.5% of the patients achieved repigmentation after grafting, and 39.28% of all patients achieved good or very good repigmentation. The results are consistent with those of previous studies 14 . In other published studies, lesions on the face and neck have shown excellent improvement with repigmentation in patients with stable vitiligo who underwent noncultured cell grafts and SEBG grafting 15,16 .…”
Section: Discussionsupporting
confidence: 91%
See 1 more Smart Citation
“…95.5% of the patients achieved repigmentation after grafting, and 39.28% of all patients achieved good or very good repigmentation. The results are consistent with those of previous studies 14 . In other published studies, lesions on the face and neck have shown excellent improvement with repigmentation in patients with stable vitiligo who underwent noncultured cell grafts and SEBG grafting 15,16 .…”
Section: Discussionsupporting
confidence: 91%
“…The results are consistent with those of previous studies. 14 In other published studies, lesions on the face and neck have shown excellent improvement with repigmentation in patients with stable vitiligo who underwent noncultured cell grafts and SEBG grafting. 15,16 Notably, due to micrograft displacement risk on the neck and other mobile areas, proper fixation of grafts is essential for successful grafting.…”
Section: Discussionmentioning
confidence: 91%
“…Lastly, 38.1% of the patients were of skin type II. Mulekar stated that skin type II shows worse results than types III‐VI due to its poor ability to tan.…”
Section: Discussionmentioning
confidence: 99%
“…But, a suspension of epidermal cells, epithelial transplantations, and cultured melanocytes are used in the newer cell‐based method, which was observed to have the advantage in skin epidermal cells over tissue in increasing therapeutic efficacy 11,12 . Moreover, the complications of using this method are acceptable and follow‐ups were associated with very good therapeutic responses at different levels 13,14 . Findings showed that in this method, the transfer of melanocyte cells from the healthy area to the lesion area has been successful and natural melanocytes of the epidermis are effective to increase the skin opacity of the lesion area by creating differentiation and production of melanin in new cells 15 .…”
Section: Introductionmentioning
confidence: 99%