Study of the oleanolic and ursolic acid contents of some species of the Lamiaceae

Janicsák, Gábor; Veres, Katalin; Kakasy, A.; Máthé, Imre

doi:10.1016/j.bse.2005.12.004

Cited by 102 publications

(56 citation statements)

References 20 publications

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“…Janicsak et al (2006) found higher amounts of oleonolic and ursolic acids in many Stachys and Salvia species. Both oleonolic acid and ursolic acid, which are rather similar because of the closeness of their chemical structures, have many important pharmacological effects.…”

Section: Discussionmentioning

confidence: 85%

Extended longevity ofDrosophila melanogasterby water and ethanol extracts ofStachys lavandulifolia

Altun

Ayar

Uysal

et al. 2010

Pharmaceutical Biology

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Section: Discussionmentioning

confidence: 85%

Extended longevity ofDrosophila melanogasterby water and ethanol extracts ofStachys lavandulifolia

Altun

Ayar

Uysal

et al. 2010

Pharmaceutical Biology

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“…Janicsak et al (2006) reported the variability in oleanolic and ursolic acid contents among subspecies of S. nemorosa. In addition, S. nemorosa is clearly separate from S. virgata, which is based on Sajadi et al (2010).…”

Section: Discussionmentioning

confidence: 99%

Chemotaxonomy and flavonoid diversity of Salvia L.(Lamiaceae) in Iran

Kharazian

2014

Acta Bot. Bras.

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In this study, we evaluated the chemotaxonomic status and chemical diversity of Salvia L. species in Iran using leaf flavonoid profiles. ; and S. hydrangea Dc. ex Benth. Two-dimensional maps of these species were created with thin-layer chromatography. In order to study the taxonomic position of these species and 37 accessions, cluster analysis was applied. The results of the cluster analysis showed that S. spinosa was distinct from S. reuterana. Despite considerable morphological similarity between S. nemorosa and S. virgata, those two species are definitely distinguished. In addition, S. spinosa and S. macrosiphon were roughly grouped, whereas S. ceratophylla and S. multicaulis composed two separate groups. In the 14 species collected, the flavonoids identified were flavones, flavonols, flavanones, isoflavones, dihydroflavonols and chalcones. We found that flavonoids are appropriate indicators to determine the taxonomic position of Salvia species.

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“…vulgaris L. (0.643% dry weight) (Janicsák et al, 2006) and dried cranberry (0.659%) (Zhang et al, 2013). The concentration of 1 ranged from trace amounts to 4.019% in 88 taxa of the Lamiacea family (Janicsák et al, 2006).…”

mentioning

confidence: 99%

“…The concentration of 1 ranged from trace amounts to 4.019% in 88 taxa of the Lamiacea family (Janicsák et al, 2006). Among natural products, the terpenoids represent a unique and most important class of bioactive compounds.…”

mentioning

confidence: 99%

Angiotensin I-Converting Enzyme (ACE) Inhibitory Activity of Ursolic Acid Isolated from Thymus vulgaris, L.

Shimada

Inagaki

2014

FSTR

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Thymus vulgaris L. (Thyme)is an aromatic medicinal herb widely used in folk medicine, as a food seasoning and herbal tea, and as an essential oil. A 70% EtOH extract from the leaves of thyme was prepared and a component was purified and characterized using an in vitro bio-assay based on the inhibition of angiotensin I-converting enzyme (ACE). Ursolic acid (1), a known pentacyclic triterpene acid, was isolated from the leaves of thyme and its structure was characterized by 1 H, 13C-NMR and 2D NMR spectroscopy, and by mass spectroscopy. Compound 1 showed an IC 50 value of 3.05 mM. This is the first study to report the ACE inhibitory activity of 1.

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Study of the oleanolic and ursolic acid contents of some species of the Lamiaceae

Cited by 102 publications

References 20 publications

Extended longevity ofDrosophila melanogasterby water and ethanol extracts ofStachys lavandulifolia

Extended longevity ofDrosophila melanogasterby water and ethanol extracts ofStachys lavandulifolia

Chemotaxonomy and flavonoid diversity of Salvia L.(Lamiaceae) in Iran

Angiotensin I-Converting Enzyme (ACE) Inhibitory Activity of Ursolic Acid Isolated from Thymus vulgaris, L.

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