-The objective of this study was to analyze the association between sleep quality, leisure-time exercise and obesity among university employees. The sample consisted of 92 adults of both genders. Sleep quality and physical activity were assessed by questionnaires. Overweight/obesity was diagnosed based on body mass index, which was calculated from self-reported measures of body weight and height. The prevalence of sleep disorders was 53.84%. An association was observed between obesity (OR = 7.22 [OR 95%CI : 1.65-31.5]) and poor sleep quality, and between physical activity and good sleep quality (OR = 0.19 [OR 95%CI : 0.04-0.95]), irrespective of other confounders. In conclusion, the results showed a high prevalence of sleep disorders, which were independently associated with physical activity and obesity. (OR= 7,22 [OR IC95% : 1,5]) e pior qualidade do sono, bem como, prática de atividade física e melhor qualidade do sono (OR= 0,19 [OR IC95% : 0,95]