2016
DOI: 10.17816/ov9458-67
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Ocular neovascular-related diseases: immunological mechanisms of development and the potential of anti-angiogenic therapy

Abstract: The paper adresses three ocular diseases - “wet” type of age-related macular degeneration, diabetic macular edema and neovascular glaucoma, which have similar neovascular changes and immunological disorders. The key moment of neovascularization development is an imbalance between pro- and anti-angiogenic factors. Particular attention is paid to vascular endothelial growth factor (VEGF-A), pigment epithelial derived factor (PEDF), transforming growth factor-beta (ТGF-β). The paper discusses the “immune privileg… Show more

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Cited by 6 publications
(2 citation statements)
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“…The authors [19] concluded that although the ICC was high, AS-OCT and UBM could not be used interchangeably for ACD measurements in pseudophakic eyes. Furthermore, Zhang [21] compared ACD measurement with AS-OCT and UBM in eyes after ICL V4 implantation. The results showed that AS-OCT slightly but significantly overestimated ACD by a mean of 0.058 mm than UBM.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The authors [19] concluded that although the ICC was high, AS-OCT and UBM could not be used interchangeably for ACD measurements in pseudophakic eyes. Furthermore, Zhang [21] compared ACD measurement with AS-OCT and UBM in eyes after ICL V4 implantation. The results showed that AS-OCT slightly but significantly overestimated ACD by a mean of 0.058 mm than UBM.…”
Section: Discussionmentioning
confidence: 99%
“…As referred to C-ICL and vault measurements comparation among AS-OCT, Pentacam and UBM, there has been limited studies so far. Zhangs’ [21] reported that AS-OCT gave a comparable C-ICL measurements but significantly higher vault measurement than UBM in eyes after ICL implantation. A significantly good correlation was found between OCT and UBM, but the 95% LoA of vault measurements indicated that the difference between these two devices was clinically unacceptable.…”
Section: Discussionmentioning
confidence: 99%