N-substituted 2,5-di(2-thienyl)pyrroles: application, production, properties, and electrochemical polymerization (review)

Abstract

In this review methods for the synthesis of substituted 2,5-di(2-thienyl)pyrroles are described, and various aspects of their application are discussed. The main emphasis is on the electrochemical behavior of the compounds, the possibility of their electrochemical polymerization, and their use as monomers for the production of conducting polymers -components for molecular electronics.

Review—Functional Platforms for (Bio)sensing: Thiophene-Pyrrole Hybrid Polymers

“…Several reviews on synthesis approaches and potential for tailordesigning the SNS structures are available. 3,23,24 The synthesis of DTP derivatives was derived from the attempt to insert a bridging unit between adjacent thiophene rings in order to add structural material and enforce planarity improving electron delocalization. 25 One of the first heteroatom-bridged molecules investigated was dithieno[3,2-b:2′,3′-d]thiophene (DTT), 26 yet its functionalization was limited, thus its analog, dithieno[3,2-b:2′,3′-d] pyrrole (DTP) became of interest.…”

Comparative investigation of spectroelectrochemical and biosensor application of two isomeric thienylpyrrole derivatives

“…Many investigators have demonstrated that covalent functionalization of conducting polymers could be obtained by synthesis of functionalized monomers bearing a prosthetic group, which are subsequently polymerised. 5 The progress of such systems strongly depends on efficient protein immobilization on polymer substrates. In order to reach this complex heterogeneous interaction the polymer surface must be functionalized with chemical groups that are reactive towards proteins in a way that surface functional groups (such as carboxyl, -COOH; amine, -NH 2 ; and hydroxyl, -OH) chemically or physically anchor the proteins to the polymer platform.…”

“…[24][25][26][27] Plenty of the primordial glucose biosensors were established on H 2 O 2 produced in the enzymatic oxidation of glucose by glucose oxidase (GOx) or amperometric determination of consumed oxygen. 5 Electrochemical amperometric biosensors are widely used class of glucose biosensing. 28,29 Fabrications of amperometric biosensors are rely on the electroactivity of the substrate or the product of the enzymatic reaction (rst generation biosensors).…”

Selective bromination of 2,5-bis(2-thienyl)pyrroles and solid-state polymerization through the β-carbon of pyrrole

“…These two points creates interesting trend in reactivity difference of a-position of thiophene and b-position of pyrrole in the S E Ar reactions. 5 Development of new processing technique to obtain the polymer with a higher degree of order has immense importance for device performance. Conjugated polymers can be directly obtained in solid state from a soluble and structurally preorganized crystalline monomer by solid-state polymerization (SSP).…”