Microwave‐Assisted Organic Synthesis: Overview of Recent Applications

Sharma, Nandini; Sharma, Upendra K.; Eycken, Erik V. Van der

doi:10.1002/9781119288152.ch17

Cited by 45 publications

(26 citation statements)

References 155 publications

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“…15,18,22 Over the past two decades, the microwave (MW) heating technique, described as "the Bunsen burner of the 21 st century", 23 has proven to be an invaluable alternative in diverse applications such as, inter alia, organic and peptide synthesis, materials science, polymers, nanotechnology and biochemical methods. 24 The advantages of MW over the conventional techniques was attributed to the fact that the former signicantly reduces the reaction time, enhances product purities and provides high yields and selectivity. 23,24 Unlike the aforementioned studies, we demonstrate here, for the rst time, a signicantly streamlined eco-friendly route for the in situ synthesis of novel cinnoline derivatives inside sporopollenin cages via a chemical reaction triggered by microwave irradiation.…”

Section: Introductionmentioning

confidence: 99%

“…24 The advantages of MW over the conventional techniques was attributed to the fact that the former signicantly reduces the reaction time, enhances product purities and provides high yields and selectivity. 23,24 Unlike the aforementioned studies, we demonstrate here, for the rst time, a signicantly streamlined eco-friendly route for the in situ synthesis of novel cinnoline derivatives inside sporopollenin cages via a chemical reaction triggered by microwave irradiation. Our approach might also bridge the revolutionised microwave assisted organic synthesis and the versatile microencapsulation capability of natural biomaterials in an effort to open up various new potential applications.…”

Section: Introductionmentioning

confidence: 99%

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Microwave assisted one-pot green synthesis of cinnoline derivatives inside natural sporopollenin microcapsules

Dyab

Sadek

2018

RSC Adv.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Microwave assisted one-pot green synthesis of cinnoline derivatives inside natural sporopollenin microcapsules

Dyab

Sadek

2018

RSC Adv.

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“…In the same vein, students might not always make accurate observations or explanations, but through active engagement 3 they become familiar with the principles of microwave-assisted organic synthesis. 36 − 38 Last but not least, compound 5 could be developed as an imaging probe or utilized in material sciences.…”

Section: Resultsmentioning

confidence: 99%

Multicomponent Reactions: “Kinderleicht”

Neochoritis

Zarganes‐Tzitzikas

Katsampoxaki-Hodgetts

et al. 2020

J. Chem. Educ.

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A demonstration experiment of the synthesis of a novel tetrazole derivative via a multicomponent reaction (Ugi tetrazole four component reaction, UT-4CR) bearing a luminol moiety and a subsequent exploitation of its chemiluminescent properties is described. A complex product is generated in just one simple step, so simple that children can do it: “kinderleicht”, German for dead easy. Students are stimulated, inspired, and involved in a multilevel active learning process using the Steps to Inquiry framework as a metacognitive tool that raises student awareness regarding scientific process and prompts them to ask their own questions discussing the merits of a mechanism and evaluating its effectiveness before they start their own cycles of inquiry.

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“…The use of microwave irradiation in cyclo-addition reactions for click chemistry has also been comprehensively deliberated. It allows efficient internal heat transfer and therefore decreases the reaction time as well as enhances the reaction rate with high yield [76][77]. The increased temperature can be used over short periods thus avoiding decomposition or polymerization.…”

Section: Microwave-assisted Click Chemistrymentioning

confidence: 99%

Role of Click Chemistry in Organic Synthesis

Sethiya¹,

Sahiba²,

Agarwal³

2021

Current Topics in Chirality - From Chemistry to Biology

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Click chemistry involves highly efficient organic reactions of two or more highly functionalized chemical entities under eco-benign conditions for the synthesis of different heterocycles. Several organic reactions such as nucleophilic ring-opening reactions, cyclo-additions, nucleophilic addition reactions, thiol-ene reactions, Diels Alder reactions, etc. are included in click reactions. These reactions have very important features i.e. high functional group tolerance, formation of a single product, high atom economy, high yielding, no need for column purification, etc. It also possesses several applications in drug discovery, supramolecular chemistry, material science, nanotechnology, etc. Being highly significant and valuable, we have elaborated on several aspects of click reactions in organic synthesis in this chapter. Recent advancements in the field of organic synthesis using click chemistry approach have been deliberated by citing last five years articles.

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Microwave‐Assisted Organic Synthesis: Overview of Recent Applications

Cited by 45 publications

References 155 publications

Microwave assisted one-pot green synthesis of cinnoline derivatives inside natural sporopollenin microcapsules

Microwave assisted one-pot green synthesis of cinnoline derivatives inside natural sporopollenin microcapsules

Multicomponent Reactions: “Kinderleicht”

Role of Click Chemistry in Organic Synthesis

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