Investigation of hair shaft in seborrheic dermatitis using atomic force microscopy

Abstract

The changes in the hair shaft affected SD was measured using AFM non-invasively. AFM could be a useful tool in monitoring the treatment response and the severity of SD.

Qualitative investigation of fresh human scalp hair with full-field optical coherence tomography

“…For a number of decades, hair fiber has been the subject of intense scientific research in dermatology and cosmetology. [1][2][3] In particular, structural characterization of hair has been of special interest because the morphological features of hair have provided important biophysical clues for early diagnosis of skin disease 4 and breast cancer, 5 cosmetic assessment, 6 and forensic examination. 7 Classically, ultrastructural observation of human hair has been widely performed by using scanning electron microscopy (SEM) and transmission electron microscopy (TEM).…”

Effects of atopic dermatitis on the morphology and water content of scalp hair

“…We did not observe significant differences in number or size of pits in AD patients compared to control hair. In a previous study, we demonstrated that pits result from crackled corneocytes in psoriatic hair (Kim et al, 2011). In contrast, it seems that the pits in AD hair are secondarily formed by holes in scale.…”

“…Very thick scales were seen in most hairs from patients with AD. Compared to previous reports describing seborrheic dermatitis and scalp psoriasis (Kim et al, 2011;Shin et al, in press), AD scales were character- ized as more elongated in shape, resembling icicles, and/or a globular, such as pepper grains.…”

“…Many studies have demonstrated that AFM is a good technique for the evaluation of surface properties of human hair (Gurden et al, 2004;LaTorre and Bhushan, 2005). Morphological changes induced in hair by diseases such as psoriasis and seborrheic dermatitis have been observed by AFM (Kim et al, 2011;Shin et al, in press). Thermal analysis is a very efficient method for studying chemical composition and thermal stability of materials.…”

Trichogram Findings in Psoriasis and Seborrheic Dermatitis Patients

“…Bu çalışmanın sonucunda, seboreik dermatit hastalığında tedavi yanıtı değerlen-dirilir iken sadece eritem, skuam ve kaşıntı gibi klinik parametrelerin değil saç şaftı değişiklikleri-nin de göz önünde bulundurulması gerektiği öne sürülmüştür. 26 Çalışmamızda da seboreik dermatit hastalarının trikogram bulguları kontrol grubuna kıyasla artmış telogen ve displastik saç oranları gös-termiş, anagen saç oranlarında azalma saptanmış-tır.…”