Effects of atopic dermatitis on the morphology and water content of scalp hair

Kim, Kyung Sook; Shin, Min Kyung; Kim, Ji Hye; Kim, Mi‐Hyun; Haw, Choong Rim; Park, Hun-Kuk

doi:10.1002/jemt.21101

Cited by 15 publications

(15 citation statements)

References 21 publications

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“…This understanding comes primarily from epidemiological studies comparing hair obtained from healthy and diseased scalps. Scalp psoriasis has been shown to result in hair with altered surface physical and chemical properties [20][21][22][23][24][25] and premature hair loss. [26][27][28] Similar observations have been made regarding the impact of dandruff and seborrheic dermatitis (D/SD) on hair physical and chemical characteristics [29][30][31][32] and hair loss.…”

Section: Introductionmentioning

confidence: 99%

Incubatory environment of the scalp impacts pre‐emergent hair to affect post‐emergent hair cuticle integrity

Schwartz

Henry

Kerr

et al. 2017

J of Cosmetic Dermatology

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SummaryObjectives: To determine whether the oxidative stress transmitted to newly grown hair from an unhealthy scalp has physical consequences to the cuticular condition and function.Methods: A uniquely designed 24-week clinical study included 8 weeks of pretreatment with a cosmetic shampoo and 16 weeks of treatment with either a potentiated zinc pyrithione (ZPT) antidandruff shampoo or a placebo cosmetic shampoo.This clinical design allowed the growth and acquisition of hair samples under conditions of varying but known scalp health as a result of treating a dandruff/seborrheic dermatitis (D/SD) population. Two complementary methods were used to characterize the integrity of the cuticular surface. Hair surface hydrophobicity was assessed by quantifying water wetting force using a Wilhelmy balance method. Surface structure and porosity were assessed using dynamic vapor sorption (DVS) to gravimetrically quantify water sorption.Results: Chemical oxidative stress to pre-emergent hair has been shown to have negative consequences to hair surface structure. Compared to a placebo shampoo control, use of a potentiated ZPT shampoo improved scalp health and significantly improved the following attributes associated with healthy hair: hair surface hydrophobicity (surface energy) and cuticular moisture barrier effectiveness (dynamic vapor sorption).Conclusions: Pre-emergent hair can be negatively impacted by the oxidative stress that occurs with an unhealthy scalp, possibly due to metabolic activity of resident microbes. Manifestations of the oxidative stress include altered cuticle surface properties that are responsible for its protective function; these effects are similar in type to those observed by bleaching post-emergent hair. These alterations have the potential to make the hair, once emerged from the scalp, more susceptible to the cumulative physical and chemical insults responsible for hair feel and look, fiber integrity, and overall retention. K E Y W O R D Sdandruff, hair quality, HODE, oxidative stress, seborrheic dermatitis Retired (NR-F).

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Section: Introductionmentioning

confidence: 99%

Incubatory environment of the scalp impacts pre‐emergent hair to affect post‐emergent hair cuticle integrity

Schwartz

Henry

Kerr

et al. 2017

J of Cosmetic Dermatology

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“…Shed vellus hairs present an alternative substrate, and P. acnes has been shown adhering to hairs within comedones [28]. Hair contains significant amounts of water [29]. …”

Section: Water and Colonisation Of The Pilosebaceous Folliclementioning

confidence: 99%

A Honey Trap for the Treatment of Acne: Manipulating the Follicular Microenvironment to ControlPropionibacterium acnes

Eady

Layton

Cove

2013

BioMed Research International

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Today, as 40 years ago, we still rely on a limited number of antibiotics and benzoyl peroxide to treat inflammatory acne. An alternative way of suppressing the growth of Propionibacterium acnes is to target the environment in which it thrives. We conjecture that P. acnes colonises a relatively “extreme” habitat especially in relation to the availability of water and possibly related factors such as ionic strength and osmolarity. We hypothesise that the limiting “nutrient” within pilosebaceous follicles is water since native sebum as secreted by the sebaceous gland contains none. An aqueous component must be available within colonised follicles, and water may be a major factor determining which follicles can sustain microbial populations. One way of preventing microbial growth is to reduce the water activity (a w) of this component with a biocompatible solute of very high water solubility. For the method to work effectively, the solute must be small, easily diffusible, and minimally soluble in sebaceous lipids. Xylose and sucrose, which fulfil these criteria, are nonfermentable by P. acnes and have been used to reduce water activity and hence bacterial colonisation of wounds. A new follicularly targeted topical treatment for acne based on this approach should be well tolerated and highly effective.

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“…As the person ages, the hair changes to be thin, gray, and dry . The hair surface is seriously damaged by disease . Psoriasis hair samples exhibited more pits than control samples and the pits were larger in size .…”

mentioning

confidence: 99%

“…The hair with SD had thick scales, which was seven‐fold more than in the control hair and the surface was rough. By atopic dermatitis (AD), the edge of the cuticle was significantly torn and collapsed . Externally, the hair was damaged by ultraviolet (UV) radiation, heat, humidity, and chemical agents .…”

mentioning

confidence: 99%

Analysis of aging effects on chemical property of human hair by Fourier transform infrared spectroscopy

Kim¹,

Park²

2012

Skin Research and Technology

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Effects of atopic dermatitis on the morphology and water content of scalp hair

Cited by 15 publications

References 21 publications

Incubatory environment of the scalp impacts pre‐emergent hair to affect post‐emergent hair cuticle integrity

Incubatory environment of the scalp impacts pre‐emergent hair to affect post‐emergent hair cuticle integrity

A Honey Trap for the Treatment of Acne: Manipulating the Follicular Microenvironment to ControlPropionibacterium acnes

Analysis of aging effects on chemical property of human hair by Fourier transform infrared spectroscopy

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