Internal Decontamination of Dental Implants: An In Vivo Randomized Microbiologic 6‐Month Trial on the Effects of a Chlorhexidine Gel

Paolantonio, Michele; Perinetti, Giuseppe; D’Ercole, Simonetta; Graziani, Filippo; Catamo, Giovanni; Sammartino, Gilberto; Piccolomini, R

doi:10.1902/jop.2008.070660

Cited by 66 publications

(74 citation statements)

References 30 publications

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“…Paolantonio et al reported that the clinical relevance of internal decontamination of implants is still to be ascertained [7]. A recent randomised double-blind clinical trial by de Waal et al attempted to determine clinical outcomes of patients with periimplantitis whose implants had been rinsed for 1 min with either 2% chlorhexidine or 0.12% chlorhexidine + 0.05% cetylpyridinium chloride [8].…”

Section: Q2mentioning

confidence: 99%

In vitro evaluation of the antibiofilm properties of chlorhexidine and delmopinol on dental implant surfaces

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Theodoridis

Green

et al. 2015

International Journal of Antimicrobial Agents

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Section: Q2mentioning

confidence: 99%

In vitro evaluation of the antibiofilm properties of chlorhexidine and delmopinol on dental implant surfaces

Ready

Theodoridis

Green

et al. 2015

International Journal of Antimicrobial Agents

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“…To calculate the sample size (n), the authors considered the expectation of the mean difference to be equal to 0.70 with an expected standard deviation of 0.80; the power of the study (1-β) was set to 0.80, and the probability of type I error (α) was set to 0.05. 15 A minimum sample size of 13 patients (n = 13) was determined (SPSS 18.0 software, SPSS Inc., Chicago, USA).…”

Section: Methodology Patient Selectionmentioning

confidence: 99%

Immediate loading implants with mandibular overdenture: a 48-month prospective follow-up study

Zancopé¹,

Júnior²,

Davi³

et al. 2014

Braz. oral res.

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The aim of this prospective clinical study was to evaluate patient rehabilitation with two immediately loaded implants and bar-retained mandibular overdentures after 48 months of follow-up. Twenty patients were treated with two implants each; of these, 17 patients were re-evaluated for comparison. Gender, age, plaque index, gingival inflammation, keratinized mucosa, probing depth, bleeding, and implant loss data were recorded, and periapical radiographs were obtained for measurement of marginal bone loss. The results were statistically analyzed with one-way analysis of variance (ANOVA) followed by Student's t-test and Pearson's correlation test. To compare the data at baseline and after 48 months, a Wilcoxon Signed Rank Test was performed (α = 0.05). One implant failed (2.9%) during the first year and was replaced. A total of 35 implants were evaluated. Bone loss values were 0.52-2.89 mm (mean, 1.46 mm). Probing depth was 1.75-3.75 mm (mean, 2.22 mm). Correlations were found between bone loss and plaque index and between bone loss and gender, but bone loss did not correlate with gingival inflammation, keratinized mucosa, probing depth, or age. The overall survival rate of the implants was 97.1%. Based on these results, the use of two immediately loaded splinted interforaminal implants to retain an overdenture with a bar attachment is a clinically viable option with a high survival rate.

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“…Gram-negative bacteria such as E. coli, used in this study, have a large size, good mobility and survive in adverse environments; they are able to infiltrate the interior of the interface between abutments and dental implants (24). A protocol to control bacteria and strategies to reduce bacterial adhesion and biofilm formation on the surfaces of fasteners during the treatment and maintenance of implants are needed to improve the long-term survival and the soft tissue health in the treatment of peri-implantitis (11). Even if the relationship between the characteristics of the surfaces and the behavior of biofilm formation has not been well defined, the surface free energy and roughness of surfaces to prevent the accumulation of biofilm are worth mentioning.…”

Section: Introductionmentioning

confidence: 99%

Analyses of Biofilm on Implant Abutment Surfaces Coating with Diamond-Like Carbon and Biocompatibility

et al. 2017

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The aim of this study was to evaluate the surface free energy (SFE), wetting and surface properties as well as antimicrobial, adhesion and biocompatibility properties of diamondlike carbon (DLC)-coated surfaces. In addition, the leakage of Escherichia coli through the abutment-dental implant interface was also calculated. SFE was calculated from contact angle values; R a was measured before and after DLC coating. Antimicrobial and adhesion properties against E. coli and cytotoxicity of DLC with human keratinocytes (HaCaT) were evaluated. Further, the ability of DLC-coated surfaces to prevent the migration of E. coli into the external hexagonal implant interface was also evaluated. A sterile technique was used for the semi-quantitative polymerase chain reaction (semi-quantitative PCR). The surfaces showed slight decreases in cell viability (p<0.05), while the SFE, R a , bacterial adhesion, antimicrobial, and bacterial infiltration tests showed no statistically significant differences (p>0.05). It was concluded that DLC was shown to be a biocompatible material with mild cytotoxicity that did not show changes in R a , SFE, bacterial adhesion or antimicrobial properties and did not inhibit the infiltration of E. coli into the abutment-dental implant interface. A n a l y s e s o f B i o f i l m o n I m p l a n t A b u t m e n t S u r f a c e s C o a t i n g w i t h D i a m o n d -L i k e C a r b o n a n d B i o c o m p a t i b i l i t y

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Internal Decontamination of Dental Implants: An In Vivo Randomized Microbiologic 6‐Month Trial on the Effects of a Chlorhexidine Gel

Abstract: The application of a 1% chlorhexidine gel seemed to be an effective method to reduce bacterial colonization of the implant cavity over a 6-month period.

Cited by 66 publications

References 30 publications

In vitro evaluation of the antibiofilm properties of chlorhexidine and delmopinol on dental implant surfaces

In vitro evaluation of the antibiofilm properties of chlorhexidine and delmopinol on dental implant surfaces

Immediate loading implants with mandibular overdenture: a 48-month prospective follow-up study

Analyses of Biofilm on Implant Abutment Surfaces Coating with Diamond-Like Carbon and Biocompatibility

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