As in a number of publications the suggested treatment of aggressive periodontitis includes the combined use of amoxicillin with metronidazole, these results highlight the need for culture and antimicrobial susceptibility investigations in patients with aggressive periodontitis prior to systemic use of antibiotics concomitantly to periodontal therapy.
Staphylococcus aureus and Candida albicans, opportunistic pathogens frequently found within denture biofilms, can cause oral and systemic infections. Parylene-C, frequently used to coat medical implant devices, may induce favourable surface alterations, potentially reducing biofilm formation on dental materials e.g. poly(methyl-methacrylate) (PMMA). This study aimed to determine if Parylene-C coated PMMA reduces MRSA and C. albicans biofilm formation. No significant difference in viable MRSA and C. albicans recovered from 48 hr single or dual species biofilms grown on PMMA or Parylene-C coated PMMA were noted, indicating that coating PMMA with Parylene-C does not reduce biofilm formation by MRSA or C. albicans.
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