HTLV-I Induced Intestinal Lymphoma

Cabrera, M E; Labra, S; Ford, Anthony M.; Matutes, Estella

doi:10.1080/10428199909169632

Cited by 4 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Finally, 90 articles were chosen including 940 ATL reported cases; 24 papers were found in the Caribbean, 15,24,25,28–48 two in Central America (Table 2) 49,50 and 64 in South America (Table 3). 9,16,51…”

Section: Resultsmentioning

confidence: 99%

“…86 In Chile, up till 2003, seven articles were published. [88][89][90][91][92][93][94] In one of them, ATL was shown as the most frequent disease (48%) among 23 T-cell mature leukemias/lymphomas. In this study, serology for HTLV-1 was only performed in indicated cases.…”

Section: Commentsmentioning

confidence: 99%

“…These age differences probably may be due to genetic or environment factors; 14 from the 22 ATL cases associated with HAM/TSP were observed in Brazil 54 but, in Chile, this association happened in 27% of the ATL cases. 93 According to Cabrera et al., 93 the reason for this association is not known but may be due to genetic and/or environment factors or the result of a careful examination of their patients. This is an exceptional association in other countries.…”

Section: Commentsmentioning

confidence: 99%

See 2 more Smart Citations

Adult T-cell leukemia/lymphoma in South and Central America and the Caribbean: systematic search and review

2016

View full text Add to dashboard Cite

Adult T-cell leukemia/lymphoma (ATL) is caused by the human T-cell lymphotropic virus type 1 (HTLV-1) which is endemic in countries of Caribbean and Central and South America. We performed a systematic search and review to identify publications on ATL in these countries to verify if this disease was getting recognition in these regions as well as the characteristics of the observed cases. The median age of 49.4 years was lower than that referred to in Japan. According to our findings in most Brazilian states and in some other countries, ATL is not being recognized and should be strongly considered in the differential diagnosis of T-cell leukemias/lymphomas. Failure to identify these cases may be due to the unsystematic realization of serology for HTLV-1 and phenotypic identification of non-Hodgkin lymphomas that may result from lack of resources. Detection of ATL cases has been more feasible with cooperation from foreign research centers. A huge effort should be made to improve the surveillance system for ATL diagnosis in most of the South- and Central-American and Caribbean countries, and this attitude should be embraced by public organs to support health professionals in this important task.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Commentsmentioning

confidence: 99%

Section: Commentsmentioning

confidence: 99%

See 1 more Smart Citation

Adult T-cell leukemia/lymphoma in South and Central America and the Caribbean: systematic search and review

2016

View full text Add to dashboard Cite

show abstract

“…As an HTLV endemic country, Peru reports large cohorts of TSP/HAM reflecting a common disease [452][453][454][455], and also cases in which HTLV infection correlates with infective dermatitis [456], including children in which neurological disorders co-exists with infective dermatitis [457] and Strongyloides stercoralis [458,459]. Fifty-four cases of ATLL have been reported from Chile [266][267][268][269][270][271][272]275]. Highlights are the early presentation, with medians of 50 yrs and 51 yrs for the largest cohorts [266,268], and an onset concomitant with or proceeded by TSP/HAM.…”

Section: Htlv Prevalence and Morbidity In Latin Americamentioning

confidence: 99%

Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED

Chabay

Lens

Hassan

et al. 2020

Cancers

View full text Add to dashboard Cite

The Epstein–Barr virus (EBV), Kaposi sarcoma herpesvirus (KSHV) and human T-lymphotropic virus (HTLV-1) are lymphomagenic viruses with region-specific induced morbidity. The RIAL-CYTED aims to increase the knowledge of lymphoma in Latin America (LA), and, as such, we systematically analyzed the literature to better understand our risk for virus-induced lymphoma. We observed that high endemicity regions for certain lymphomas, e.g., Mexico and Peru, have a high incidence of EBV-positive lymphomas of T/NK cell origin. Peru also carries the highest frequency of EBV-positive classical Hodgkin lymphoma (HL) and EBV-positive diffuse large B cell lymphoma, not otherwise specified (NOS), than any other LA country. Adult T cell lymphoma is endemic to the North of Brazil and Chile. While only few cases of KSHV-positive lymphomas were found, in spite of the close correlation of Kaposi sarcoma and the prevalence of pathogenic types of KSHV. Both EBV-associated HL and Burkitt lymphoma mainly affect young children, unlike in developed countries, in which adolescents and young adults are the most affected, correlating with an early EBV seroconversion for LA population despite of lack of infectious mononucleosis symptoms. High endemicity of KSHV and HTLV infection was observed among Amerindian populations, with differences between Amazonian and Andean populations.

show abstract

“…Therefore, the patient's diagnosis was stage IIE (Lugano classification) small-bowel adult T-cell leukemia/lymphoma (ATLL) accompanied by gastric AL amyloidosis. Although systemic ATLL often involves the small bowel [1 -3], primary small-bowel ATLL is extremely rare [4,5]. Endoscopic findings of small-bowel involvement with ATLL have included multiple polypoid or reddish elevated lesions [2,3].…”

mentioning

confidence: 99%

Primary small-bowel adult T-cell leukemia/lymphoma with gastric AL amyloidosis

et al. 2014

View full text Add to dashboard Cite

An 86-year-old man was admitted because of small-bowel wall thickening and mesenteric lymphadenopathy. Neither peripheral lymphadenopathy nor hepatosplenomegaly was noted. The leukocyte count was 7930/mm 3 , and no abnormal lymphocytes were found. The result of testing for serum antihuman T-lymphotropic virus type 1 (HTLV-1) antibody was positive. A bone marrow biopsy was normal without evidence of lymphoid infiltration. Smallbowel enteroclysis demonstrated a narrowing, edematous lesion with multiple ulcerations in the jejunum (• " Fig. 1). Capsule endoscopy (• " Fig. 2) and doubleballoon endoscopy (• " Fig. 3) showed enlarged Kerckring folds with annular and irregularly shaped shallow ulcers. Biopsy specimens from the ulcers revealed diffuse infiltration of medium to large pleomorphic lymphoid cells with CD3 +, CD4 +, CD5 +, CD25 +, CCR4 +, FoxP3 +, CD8-, CD20-, CD56-, and TIA1immunophenotype (• " Fig. 4). Biopsy specimens from the stomach, duodenum, ileum, and colon showed no lymphoma cells. Fluorodeoxyglucose F 18 positron emission tomography showed abnormal uptake in the jejunal mass, wide areas of mesentery, and Cases and Techniques Library (CTL) E613 Yaita Hiroki et al. Small-bowel adult T-cell leukemia/lymphoma with gastric AL amyloidosis … Endoscopy 2014; 46: E613-E614

show abstract

HTLV-I Induced Intestinal Lymphoma

Cited by 4 publications

References 7 publications

Adult T-cell leukemia/lymphoma in South and Central America and the Caribbean: systematic search and review

Adult T-cell leukemia/lymphoma in South and Central America and the Caribbean: systematic search and review

Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED

Primary small-bowel adult T-cell leukemia/lymphoma with gastric AL amyloidosis

Contact Info

Product

Resources

About