Frequency of septum pellucidum anomalies in non-psychotic population: a magnetic resonance imaging study

Abstract

This prospective MRI investigation was performed to investigate septum pellucidum (SP) anomalies in 505 (242 male, 263 female) non-psychotic persons. The mean age of the population was 39.179 +/- 0.904 (40.461 +/- 1.395 male, 38 +/- 1.166 female). There was no significant difference between the means of age in the male and female groups (t-test, DF = 479, p > 0.05). The SP anomalies were classified as cavitation anomalies (Type I) and absence of the SP (Type II). Type I anomalies were subdivided into four groups as isolated cavum septi pellucidi (Ia), cavum septi pellucidi et cavum vergae (Ib), anterior small triangular cavities (Ic), and cysts of the SP (Id). The incidences of the anomalies (Type I + Type II) were 17.31%, 1.89%, 7.55%, 3.53%, 7%, 4.55%, 4.76% and 6.06% for the age groups of 0-9, 10-19, 20-29, 30-39, 40-49, 50-59, 60-69 and 70-79 years respectively. The anomalies were very significantly more frequent in the 0-9 years age group than in the other age groups (chi 2 = 9.7858, DF = 1, p < 0.05). The incidences of the anomalies (Type I + Type II) were 6.34%, 5.37%, 7.22% for the whole, male, and female populations, respectively. These values were 1.39%, 1.65% and 1.14% for Type Ia, 2.77%, 2.89% and 2.66% for Type Ib, and 1.78%, 0.83% and 2.66% for Type Ic. Both Type Id and II anomalies were determined in only one case for each group in females (0.2%). There was no significant difference between the incidences of the anomalies in both sexes (chi 2 = 0.45, DF = 1, p > 0.05).

Linear parameters of normal and abnormal cava septi pellucidi: A post‐mortem study

“…Kwon et al (1998) argue that the prevalence of CSP is 85% among normal individuals, the highest prevalence observed in the available literature. As opposed to these figures, Aldur et al (1999) reported CSP appearance of not exceeding 1.56% in life-long MRI studies of a non-psychotic population. Congruently, Pauling et al (1998) claimed that most of the non-invasive imaging methods (CT and MRI) provided studies comprised of seriously biased populations.…”

Large cava septi pellucidi in schizophrenic patients, alcoholics, head-traumatized, and normal individuals: morpholgical features and forensic implications. A postmortem study

“…Kwon and his associates (1998; 19) argued about the prevalence of 85% among normal individuals, which was the highest prevalence in the available literature. As opposed to these figures, Aldur et al (1999; 28) reported CSP appearance not exceeding 1.56% in life‐long MRI studies of a nonpsychotic population. Congruently, Pauling et al (1998; 29) claimed that most of the noninvasive imaging methods (CT and MRI) provided studies composed of seriously biased populations.…”

MR and CT of Brain's Cava

“…The velum interpositum (VI) is a triangular fold of the pia mater (tela choroidea) occupying the transverse cerebral fissure (choroidal fissure) between the diencephalon and the corpum callosum 34 . The VI is located caudal to the interventricular foramen and is interposed between the roof of the thalamus and third ventricle below and the corpus callosum and fornix above.…”